Tight Junctions of the Blood–Brain Barrier

被引：29

作者：

Uwe Kniesel

Hartwig Wolburg

机构：

[1] University of Tübingen,Institute of Pathology

来源：

Cellular and Molecular Neurobiology | 2000年 / 20卷

关键词：

tight junction; blood–brain barrier; morphology; freeze–fracture; cadherins; catenins; occludin; cytoskeleton;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

1. The blood–brain barrier is essential for the maintainance and regulation of the neural microenvironment. The blood–brain barrier endothelial cells comprise an extremely low rate of transcytotic vesicles and a restrictive paracellular diffusion barrier. The latter is realized by the tight junctions between the endothelial cells of the brain microvasculature, which are subject of this review. Morphologically, blood–brain barrier-tight junctions are more similar to epithelial tight junctions than to endothelial tight junctions in peripheral blood vessels.

引用

页码：57 / 76

页数：19

共 465 条

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