Epidemiology and pathophysiology of osteoporosis in men

被引:8
作者
Adler R.A. [1 ]
机构
[1] Endocrinology and Metabolism, McGuire Veterans Affairs Medical Center, Richmond, VA 23249
关键词
Bone Mineral Density; Osteoporosis; Testosterone; Diffuse Idiopathic Skeletal Hyperostosis; Forearm Bone Mineral Density;
D O I
10.1007/s11914-996-0030-5
中图分类号
学科分类号
摘要
Osteoporosis in men is an unrecognized but growing problem as the number of men who live to old age increases. The 10-year fracture risk at age 50 quadruples by age 80, and in general the incidence rate of osteoporotic fracture in men is about half that of women. Of note, the mortality and morbidity after hip fracture are much greater in men. There are many men whose osteoporosis is the result of specific causes such as oral glucocorticoid therapy, hypogonadism, or androgen withdrawal therapy for prostate cancer. In addition there are several interesting syndromes of osteoporosis in middle-aged men; these men usually present with vertebral fractures. As knowledge about the prevalence and etiology of osteoporosis in men increases, it will be recognized and treated in more men, in hopes of preventing fracture. Copyright © 2006 by Current Science Inc.
引用
收藏
页码:110 / 115
页数:5
相关论文
共 49 条
[1]
Kanis J.A., Johnell O., Oden A., Et al., Long-term risk of osteoporotic fracture in Malmo, Osteoporos Int, 11, pp. 669-674, (2000)
[2]
Jones G., Nguyen T., Sambrook P.N., Et al., Symptomatic fracture incidence in elderly men and women: The Dubbo Osteoporosis Epidemiology Study (DOES), Osteoporos Int, 4, pp. 277-282, (1994)
[3]
Block J.E., Stubbs H., Hip fracture-associated mortality reconsidered, Calcif Tissue Int, 61, (1997)
[4]
Tracy J.K., Meyer W.A., Grigoryan M., Et al., Racial differences in the prevalence of vertebral fractures in older men: The Baltimore Men's Osteoporosis Study, Osteoporos Int, 17, pp. 99-104, (2006)
[5]
Selby P.L., Davies M., Adams J.E., Do men and women fracture bones at similar bone densities?, Osteoporos Int, 11, pp. 153-157, (2000)
[6]
ISCD Official Positions
[7]
Looker A.C., Orwoll E.S., Johnston Jr. C.C., Et al., Prevalence of low femoral bone density in older U.S. adults from NHANES III, J Bone Miner Res, 12, pp. 1761-1768, (1997)
[8]
Schuit S.C.E., Van Der Klift M., Weel A.E.A.M., Et al., Fracture incidence and association with bone mineral density in elderly men and women: The Rotterdam Study, Bone, 34, pp. 195-202, (2004)
[9]
Melton III L.J., Atkinson E.J., O'Connor M.K., Et al., Bone density and fracture risk in men, J Bone Miner Res, 13, pp. 1915-1923, (1998)
[10]
Tuck S.P., Raj N., Summers G.D., Is distal forearm fracture in men due to Osteoporosis?, Osteoporos Int, 13, pp. 630-636, (2002)