Pulmonary involvement in leptospirosis

被引：42

作者：

Martínez García M.A. ^{[1
]}

De Diego Damiá A. ^{[1
]}

Villanueva R.M. ^{[1
]}

López Hontagas J.L. ^{[2
]}

机构：

[1] Pneumology Service, Hosp. Univ. La Fe Ave. de Campanar

[2] Microbiology Service, Hospital Universitario La Fe, Valencia

来源：

European Journal of Clinical Microbiology and Infectious Diseases | 2000年 / 19卷 / 6期

关键词：

Cigarette Smoking; Respiratory Distress; Respiratory Distress Syndrome; Distress Syndrome; Respiratory Symptom;

D O I：

10.1007/s100960000294

中图分类号：

学科分类号：

摘要：

The objective of this study was to assess the pulmonary involvement in a cohort of 26 patients in whom a diagnosis of leptospirosis had been made. Seventeen of the 26 patients had respiratory symptoms. Of these 17 patients, 13 had radiographs showing pulmonary abnormality. The most frequent finding was a bilateral patchy alveolar-acinar pattern in six patients. Three patients developed acute respiratory distress syndrome and died due to multiorgan failure. Only cigarette smoking was significantly associated with respiratory involvement (odds ratio, 19.2; 95% CI, 1.7-250; P < 0.001). The results indicate that pulmonary manifestations are observed in a high percentage of patients with leptospirosis. Cigarette smoking is a risk factor for the development of pulmonary involvement in human leptospirosis.

引用

页码：471 / 474

页数：3

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