Vaginal microbiota in healthy pregnant women and prenatal screening of group B streptococci (GBS)

被引:39
作者
Bayó M. [1 ]
Berlanga M. [2 ]
Agut M. [3 ]
机构
[1] Laboratori d'Anàlisis M. Bayó Boada, 08221 Terrassa
[2] Departament de Microbiologia i Parasitologia Sanitàries, Universitat de Barcelona
[3] Institut Químic de Sarrià, 08017 Barcelona
关键词
Group B streptococci; Pregnancy; Prenatal screening; Vaginal swabs; β-Hemolytic streptococci;
D O I
10.1007/s10123-002-0064-1
中图分类号
学科分类号
摘要
The microbiota of the lower female genital tract was evaluated from vaginal swabs obtained from 623 healthy pregnant women at gestation periods of 35-40 weeks. Isolated and identified microorganisms were expressed as percentages of total samples. As expected, lactobacilli made up the dominant vaginal microbiota (70%). Enterobacteriaceae, mainly Escherichia coli, Klebsiella spp. and Proteus, were present in 38% of the samples, which might reflect the possible contamination of vaginal tract with rectal microorganisms. Candida albicans was present in 10% of healthy pregnant woman assayed. Streptoccocci (Streptococcus sp. and Enterococcus faecalis with 3% and 4%, respectively) and other gram-positive cocci (Staphylococcus sp., 5%), along with other microorgansisms such as Gardnerella vaginalis (5%) and Pseudomonas aeruginosa (2%) may represent a potential infection risk. Streptococcus agalactiae (group B streptococci β-hemolytic, GBS) was detected in 7% of the samples. GBS infection is a leading cause of neonatal morbidity and mortality in the developed world. Furthermore, GBS was often co-isolated with C. albicans (54.5%) in the samples. A complete and detailed evaluation of the vaginal biota swab, with particular attention to the presence of potential pathogens such as GBS, is a preventive strategy that can provide useful information to obstetricians and gynecologist in managing the last days of pregnancy and delivery. © Springer-Verlag and SEM 2002.
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页码:87 / 90
页数:3
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