Video-assisted thoracic surgery lobectomy reduces the morbidity after surgery for stage I non-small cell lung cancer

被引：64

作者：

Muraoka M. ^{[1
,2
]}

Oka T. ^{[1
]}

Akamine S. ^{[1
]}

Tagawa T. ^{[1
]}

Nakamura A. ^{[1
]}

Hashizume S. ^{[1
]}

Matsumoto K. ^{[1
]}

Araki M. ^{[1
]}

Tagawa Y. ^{[1
]}

Nagayasu T. ^{[1
]}

机构：

[1] Division of Surgical Oncology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki

[2] Department of Chest Surgery, Oita Prefectural Hospital, Oita 870-8511

来源：

The Japanese Journal of Thoracic and Cardiovascular Surgery | 2006年 / 54卷 / 2期

关键词：

Lung cancer; Operative morbidity; Video-assisted thoracic surgery;

D O I：

10.1007/BF02744600

中图分类号：

学科分类号：

摘要：

Objective: We conducted this study to evaluate the surgical invasiveness and the safety of video-assisted thoracic surgery lobectomy for stage I lung cancer. Methods: Video-assisted thoracic surgery lobectomies were performed on 43 patients with clinical stage IA non-small cell lung cancer. We compared the surgical invasiveness parameters with 42 patients who underwent lobectomy by conventional thoracotomy. Results: Intraoperative blood loss was significantly less than that in the conventional thoracotomy group (151±149 vs. 362±321 g, p<0.01). Chest tube duration (3.0±2.1 vs. 3.9±1.9 days) was significantly shorter than those in the conventional thoracotomy group (p<0.05). The visual analog scale which was evaluated as postoperative pain level on postoperative day 7, maximum white blood count and C-reactive protein level were significantly lower than those in the conventional thoracotomy group (p<0.05). The morbidity rate was significantly lower than that in the conventional thoracotomy group (25.6% vs. 47.6%, p<0.05). Sputum retention and arrhythmia were significantly less frequent than in the conventional thoracotomy group (p<0.05). We experienced no operative deaths in both groups. Conclusion: We conclude that video-assisted thoracic surgery lobectomy for stage I non-small cell lung cancer patients is a less invasive and safer procedure with a lower morbidity rate compared with lobectomy by thoracotomy.

引用

页码：49 / 55

页数：6

共 23 条

[1]

Kirby T.J., Rice T.W., Thoracoscopic lobectomy, Ann Thorac Surg, 56, pp. 784-786, (1993)

[2]

Gharagozloo F., Tempesta B., Margolis M., Alexander E.P., Video-assisted thoracic surgery lobectomy for stage I lung cancer, Ann Thorac Surg, 76, pp. 1009-1015, (2003)

[3]

McKenna Jr. R.J., Thoracoscopic lobectomy with mediastinal sampling in 80-year-old patients, Chest, 106, pp. 1902-1904, (1994)

[4]

Koizumi K., Haraguchi S., Hirata T., Hirai K., Mikami I., Fukushima M., Et al., Video-assisted lobectomy in elderly lung cancer patients, Jpn J Thorac Cardiovasc Surg, 50, pp. 15-22, (2002)

[5]

Nomori H., Horio H., Naruke T., Suemasu K., What is the advantage of a thoracoscopic lobectomy over a limited thoracotomy procedure for lung cancer surgery?, Ann Thorac Surg, 72, pp. 879-884, (2001)

[6]

Nagahiro I., Andou A., Aoe M., Sano Y., Date H., Shimizu N., Pulmonary function, postoperative pain, and serum cytokine level after lobectomy: A comparison of VATS and conventional procedure, Ann Thorac Surg, 72, pp. 362-365, (2001)

[7]

Yim A.P., Wan S., Lee T.W., Arifi A.A., VATS lobectomy reduces cytokine responses compared with conventional surgery, Ann Thorac Surg, 70, pp. 243-247, (2000)

[8]

Sugi K., Kaneda Y., Esato K., Video-assisted thoracoscopic lobectomy reduces cytokine production more than conventional open lobectomy, Jpn J Thorac Cardiovasc Surg, 48, pp. 161-165, (2000)

[9]

Nakagoe T., Sawai T., Tsuji T., Nanashima A., Jibiki M., Yamaguchi H., Et al., Minilaparotomy wound edge protector (Lap-Protector): A new device, Surg Today, 31, pp. 850-852, (2001)

[10]

Hazelrigg S.R., Landreneau R.F., Boley T.M., Priesmeyer M., Schmaltz R.A., Nawarawong W., Et al., The effect of muscle-sparing versus standard posterolateral thoracotomy on pulmonary function, muscle strength, and postoperative pain, J Thorac Cardiovasc Surg, 101, pp. 394-401, (1991)

← 1 2 3 →