Diabetes mellitus and other metabolic disturbances induced by atypical antipsychotic agents.

被引：20

作者：

Henderson D.C. ^{[1
]}

机构：

[1] Massachusetts General Hospital, Freedom Trail Clinic, 25 Staniford Street, Boston, 02114, MA

来源：

Current Diabetes Reports | 2002年 / 2卷 / 2期

关键词：

Schizophrenia; Clozapine; Risperidone; Olanzapine; Quetiapine;

D O I：

10.1007/s11892-002-0072-8

中图分类号：

学科分类号：

摘要：

Atypical antipsychotic agents offer significant advantages over older conventional antipsychotic agents. The reduction in antipsychotic drug-associated extrapyramidal symptoms and the potential reduced risk for tardive dyskinesia, compared to conventional drugs, are major advances in the treatment of psychotic patients. However, recent reports of hyperglycemia, new-onset diabetes mellitus, diabetic ketoacidosis, weight gain, and lipid abnormalities associated with atypical antipsychotic agents have emerged. A review of the recent literature and an approach to the evaluation of risk factors to aide in the safe use of atypical antipsychotic agents in presented.

引用

页码：135 / 140

页数：5

共 140 条

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