Community-acquired methicillin-resistant Staphylococcus aureus: Epidemiology and potential virulence factors

被引:31
作者
Jose M. Eguia
Henry F. Chambers
机构
[1] University of California,Division of Infectious Diseases, San Francisco General Hospital
关键词
Staphylococcus Aureus; SCCmec Type; Infect Control Hosp; SCCmec Element; Phylococcus Aureus;
D O I
10.1007/s11908-003-0087-6
中图分类号
学科分类号
摘要
Methicillin-resistant Staphylococcus aureus (MRSA) has been isolated from patients in the community. Some of these strains may have origins in the hospital, but others appear to be novel and unrelated to known hospital strains. Community MRSA strains have several distinguishing characteristics that may enable them to more readily colonize and infect otherwise healthy individuals. This article reviews recent publications addressing the epidemiology of MRSA in the community, risk factors associated with carriage, potentially associated virulence factors, and concepts of strain fitness as they pertain to MRSA. MRSA likely will be an increasingly important pathogen in the community.
引用
收藏
页码:459 / 466
页数:7
相关论文
共 178 条
  • [1] Chambers HF(2001)The changing epidemiology of Staphylococcus aureus Emerg Infect Dis 7 1-5
  • [2] Hiramatsu K(2001)The emergence and evolution of methicillin-resistant Staphylococcus aureus Trends Microbiol 9 486-493
  • [3] Longzhu C(2002)New trends in Staphylococcus aureus infections: glycopeptide resistance in hospital and methicillin resistance in the community Curr Opin Infect Dis 15 407-413
  • [4] Kuroda M(2002)Dissemination of new methicillin-resistant Staphylococcus aureus clones in the community J Clin Microbiol 40 4289-4294
  • [5] Ito T(2003)Staphylococcal resistance revisited: community-acquired methicillin-resistant Staphylococcus aureus-an emerging problem for the management of skin and soft tissue infections Curr Opin Infect Dis 16 103-124
  • [6] Hiramatsu K(1988)CDC definitions for nosocomial infections, 1988 Am J Infect Control 16 128-140
  • [7] Okuma K(2002)Reappraisal of community-acquired bacteremia: A proposal for a new classification for the spectrum of acquisition of bacteremia Clin Infect Dis 34 1431-1439
  • [8] Ma XX(2003)Communityacquired-methicillin-resistant Staphylococcus aureus: an emerging pathogen Infect Control Hosp Epidemiol 24 451-455
  • [9] Okuma K(2003)Community-acquired methicillin-resistant Staphylococcus aureus: A meta-analysis of prevalence and risk factors Clin Infect Dis 36 131-139
  • [10] Iwakawa K(2000)Community acquisition of gentamicin-sensitive methicillin-resistant Staphylococcus aureus in southeast Queensland, Australia J Clin Microbiol 38 3926-3931