Peripheral body fat has a protective role on bone mineral density in elderly women

被引:8
作者
Del Puente A. [1 ,4 ]
Postiglione A. [2 ]
Esposito-del Puente A. [3 ]
Carpinelli A. [1 ]
Romano M. [2 ]
Oriente P. [1 ]
机构
[1] Department of Rheumatology, University Federico II
[2] Department of Geriatric, University Federico II
[3] Clinical Nutrition Unit, Dept. of Clin./Experimental Medicine, University Federico II
[4] Cattedra di Reumatologia, Università Federico II, 80131 Napoli, Policlinico Nuovo
关键词
Body fat; Bone mineral density; Institutionalised subjects;
D O I
10.1038/sj.ejcn.1600630
中图分类号
学科分类号
摘要
Objectives: To determine whether bone mineral density is lower in women living in homes for the elderly as compared to free dwelling control subjects, and to investigate factors affecting possible differences. This is the first study with this objective as the primary aim. Design: Case-control study. Subjects and methods: Institutionalised independent elderly women (n = 22, mean age = 75.1 y ± 6.43 s.d.) randomly selected in a home for the elderly and 22 age-marched control women randomly selected from a sample representative of the independent non institutionalised local population who underwent dual energy X-ray absorptiometry (DXA) at the lumbar spine and right femoral neck; anthropometric measurements (height, weight, subscapular and triceps skinfold thickness); general questionnaire. Results: Mean bone mineral density at the femoral neck was 0.618 g/cm2 (± 0.130 s.d.) in institutionalised women and 0.709 g/cm2 (± 0.106 s.d.) in controls (P = 0.02, t-test). Controlling for confounding factors in the analysis of covariance, triceps skinfold thickness and living in a home for the elderly turned out to be significant determinants of bone mineral density. Conclusion: When compared to free dwelling control subjects, institutionalised women show lower bone density that is the main risk factor for fracture. Reduced peripheral body fat was significantly associated with the low bone mineral density observed. Health programs aimed at decreasing the incidence of fractures among institutionalised subjects will also have to consider the effect of nutritional or life style factors that reduce peripheral body fat.
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页码:690 / 693
页数:3
相关论文
共 30 条
[1]  
Avioli L.V., Significance of osteoporosis: A growing international health care problem, Calcif. Tissue Int., 49, SUPPL., (1991)
[2]  
Barzel U.S., Estrogens in the prevention and treatment of post-menopausal osteoporosis: A review, Am. J. Med., 85, pp. 847-850, (1988)
[3]  
Carnovale E., Miuccio F., Tabelle Di Composizione Degli Alimenti, (1989)
[4]  
Cronk C.E., Roche A.F., Race- and sex-specific reference data for triceps and subscapular skinfolds and weight/stature<sup>2</sup>, Am. J. Clin. Nutr., 35, pp. 347-354, (1982)
[5]  
Del Puente A., Heyse S.P., Mandes M.G., Mantova D., Carpinelli A., Nutile G., Oriente P., Epidemiology of osteoporosis in women in Southern Italy, Aging Clin. Exp. Res., 10, pp. 53-58, (1998)
[6]  
Dequeker J., Raspe H.H., Sambrook P., Osteoporosis. Risk factors, Rheumatology, pp. 7326-7326, (1994)
[7]  
Deurenberg P., Weststrate J.A., Seidell J.C., Body mass index as a measure of body fatness: Age and sex-specific prediction formulas, Br. J. Nutr., 65, pp. 105-114, (1991)
[8]  
Esposito-del Puente A., Del Puente A., Carpinelli A., Pontillo M., Di Gioia L., Oriente P., Apporto di calcio alimentare nella popolazione adulta femminile, Reumatismo, 47, SUPPL. 2, (1995)
[9]  
Fisher E.S., Baron J.A., Malenka D.J., Barren J.A., Kniffin W.D., Whaley F.S., Bubolz T.A., Hip fracture incidence and mortality in New England, Epidemiology, 2, pp. 116-122, (1991)
[10]  
Galvard H., Elmstahl S., Elmstahl B., Samuelsson S.M., Robertsson E., Differences in body composition between female geriatric hip fracture patients and healthy controls: Body fat is more important as explanatory factor for the fracture than body weight and lean body mass, Aging Clin. Exp. Res., 8, pp. 282-286, (1996)