Parvoviral infection associated with increased nuchal translucency: A case report

被引：16

作者：

Markenson G. ^{[1
,5
]}

Correia L.A. ^{[2
]}

Cohn G. ^{[1
,3
,4
]}

Bayer L.

Kanaan C. ^{[1
]}

机构：

[1] Division of Maternal-Fetal Medicine, Baystate Medical Center, Springfield, MA

[2] Division of Reproductive Genetics, Baystate Medical Center, Springfield, MA

[3] Dept. of Obstetrics and Gynecology, Baystate Medical Center, Springfield, MA

[4] Renal Division, Brighton and Women's Hospital, Boston, MA

[5] Division of Maternal-Fetal Medicine, Baystale Medical Center, Springfield, MA 01199

来源：

Journal of Perinatology | 2000年 / 20卷 / 2期

关键词：

D O I：

10.1038/sj.jp.7200286

中图分类号：

学科分类号：

摘要：

An increased fetal nuchal translucency detected by first trimester ultrasound has been associated with an elevated risk of aneuploidy. The etiology of the increased nuchal translucency in fetuses with normal chromosomes is uncertain, but it has been associated with poor pregnancy outcome. We report a fetus with increased nuchal translucency and a normal karyotype, in which parvovirus was detected by polymerase chain reaction in the amniotic fluid. Although an ultrasound detected an increased nuchal fold thickness in the second trimester, the pregnany was otherwise uncomplicated. Parvovirus should be considered as a possible etiology of increased nuchal translucency. The risks to a fetus with first trimester parvovirus infections diagnosed under these conditions are uncertain and require larger studies.

引用

页码：129 / 131

页数：2

共 13 条

[1]

Pandya P.P., Brizot M.L., Kuhn P., Snijders R.J.M., Nicolaides K.H., First-trimester fetal nuchal translucency thickness and risk for trisomies, Obstet Gynecol, 84, pp. 420-423, (1994)

[2]

Pandya P.P., Snijders R.J., Johnson S.P., De Lourdes Brizot M., Nicolaides K.H., Screening for fetal trisomies by maternal age and fetal nuchal translucency thickness at 10 to 14 weeks of gestation, Br J Obstet Gynaecol, 103, pp. 957-962, (1995)

[3]

Reynders C.S., Pauker S.P., Benacerraf B.R., First trimester isolated fetal nuchal lucency: Significance and outcome, J Ultrasound Med, 16, pp. 101-105, (1997)

[4]

Greco P., Loverro G., Vimercati A., Marzullo A., Caruso G., Selvaggi L., Pathological significance of first-trimester fetal nuchal oedema, Prenat Diagn, 16, pp. 503-509, (1996)

[5]

Hyett J., Moscoso G., Papapanagiotou G., Perdu M., Nicolaides K.H., Abnormalities of the heart and great arteries in chromosomally normal fetuses with increased nuchal translucency thickness at 11-13 weeks of gestation, Ultrasound Obstet Gynecol, 7, pp. 245-250, (1996)

[6]

Sebire N.J., Bianco D., Snijders R.J.M., Zuckerman M., Nicolaides K.H., Increased fetal nuchal translucency thickness at 10-14 weeks: Is screening for maternal-fetal infection necessary?, Br J Obstet Gynaecol, 104, pp. 212-215, (1997)

[7]

Jordan J.A., Identification of human parvovirus B19 infection in idiopathic nonimmune hydrops fetalis, Am J Obstet Gynecol, 174, pp. 37-42, (1996)

[8]

Petrikovsky B.M., Baker D., Schneider E., Fetal hydrops secondary to human parvovirus infection in early pregnancy, Prenat Diagn, 16, pp. 342-344, (1996)

[9]

Rogers B.B., Singer D.B., Mak S.K., Gary G.W., Fikrig M.K., McMillan P.N., Detection of human parvovirus B19 in early spontaneous abortuses using serology, histology, electron microscopy, in situ hybridization, and the polymerase chain reaction, Obstet Gynecol, 82, pp. 402-408, (1993)

[10]

Cha'ban F.K., Van Splunder P., Los F.J., Wladimiroff J.W., Fetal outcome in nuchal translucency with emphasis on normal fetal karyotype, Prenat Diagn, 16, pp. 537-541, (1996)

← 1 2 →