Long-term outcomes from sepsis

被引：71

作者：

Yende S. ^{[1
]}

Angus D.C. ^{[1
]}

机构：

[1] Department of Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261

来源：

Current Infectious Disease Reports | 2007年 / 9卷 / 5期

关键词：

Severe Sepsis; Acute Respiratory Distress Syndrome; Critical Illness; Continuous Renal Replacement Therapy; Chronic Health Condition;

D O I：

10.1007/s11908-007-0059-3

中图分类号：

学科分类号：

摘要：

Long-term mortality following severe sepsis is high, and fewer than half of patients who experience severe sepsis are alive at 1 year. Mechanisms underlying increased long-term mortality remain poorly understood. Animal and human studies suggest that abnormalities of the innate immune system may contribute to increased long-term mortality. This review article examines the epidemiology and potential mechanisms underlying long-term outcomes from sepsis and challenges to conducting long-term outcome studies in the critically ill. Copyright © 2007 by Current Medicine Group LLC.

引用

页码：382 / 386

页数：4

共 23 条

[1]

Angus D.C., Carlet J., Brussels Roundtable Participants: Surviving intensive care: a report from the 2002 Brussels Roundtable, Intensive Care Med, 2003, 29, pp. 368-377, (2002)

[2]

Levy M.M., Fink M.P., Marshall J.C., Et al., SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference, Crit Care Med, 31, pp. 1250-1256, (2001)

[3]

Steinberg K.P., Hudson L.D., Goodman R.B., Et al., Efficacy and safety of corticosteroids for persistent acute respiratory distress syndrome, N Engl J Med, 354, pp. 1671-1684, (2006)

[4]

Quartin A.A., Schein R.M., Kett D.H., Peduzzi P.N., Magnitude and duration of the effect of sepsis on survival. Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group, JAMA, 277, pp. 1058-1063, (1997)

[5]

Kaplan V., Clermont G., Griffin M.F., Et al., Pneumonia: Still the old man's friend?, Arch Intern Med, 163, pp. 317-323, (2003)

[6]

LaCroix A.Z., Lipson S., Miles T.P., White L., Prospective study of pneumonia hospitalizations and mortality of U.S. older people: The role of chronic conditions, health behaviors, and nutritional status, Public Health Rep, 104, pp. 350-360, (1989)

[7]

Brancati F.L., Chow J.W., Wagener M.M., Et al., Is pneumonia really the old man's friend? Two-year prognosis after community-acquired pneumonia, Lancet, 342, pp. 30-33, (1993)

[8]

Koivula I., Sten M., Makela P.H., Prognosis after community-acquired pneumonia in the elderly: A population-based 12-year follow-up study, Arch Intern Med, 159, pp. 1550-1555, (1999)

[9]

Waterer G.W., Kessler L.A., Wunderink R.G., Medium-term survival after hospitalization with community-acquired pneumonia, Am J Respir Crit Care Med, 169, pp. 910-914, (2004)

[10]

Yende S., Angus D.C., Ali I.S., Et al., Influence of comorbid conditions on long-term mortality after pneumonia in older people, J Am Geriatr Soc, 55, pp. 518-525, (2007)

← 1 2 3 →