The relationship of bile duct crystals to sphincter of Oddi dysfunction

被引:16
作者
James Y. Rhee
Grace H. Elta
机构
[1] Division of Gastroenterology, University of Michigan, Ann Arbor, MI 48109-0362
关键词
Bile Duct; Ursodeoxycholic Acid; Bile Duct Stone; Endoscopic Sphincterotomy; Gallbladder Stone;
D O I
10.1007/s11894-003-0086-7
中图分类号
学科分类号
摘要
Bile duct crystals collected either from the duodenum after gallbladder contraction or directly from bile duct aspiration are surrogates for gallbladder stones and microlithiasis. Whether bile crystals also serve as surrogates for bile duct stones or microlithiasis that forms in the bile duct after cholecystectomy is not known based on current data. Sphincter of Oddi dysfunction (SOD), due either to muscular spasm or sphincter fibrosis, is a cause of bile duct obstruction. Almost all of the literature on SOD involves patients who have had a prior cholecystectomy, Intuitively, obstruction at the SO following cholecystectomy would seem to lead to biliary stasis and predispose patients to bile duct microlithiasis. However, a recent study did not find bile duct crystals in patients with manometrically diagnosed SOD. The reason for this is unknown, although we hypothesize that cholesterol and bilirubinate crystals are not surrogates for brown pigment stones commonly found in patients following cholecystectomy. Copyright © 2003 by Current Science Inc.
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收藏
页码:160 / 163
页数:3
相关论文
共 23 条
[1]
Lee S.P., Maher K., Nicholls J.F., Origin and fate of biliary sludge, Gastroenterology, 94, pp. 170-176, (1988)
[2]
Ros E., Navarro S., Bru C., Et al., Occult microlithiasis in 'idiopathic' acute pancreatitis: Prevention of relapses by cholecystectomy or ursodeoxycholic acid therapy, Gastroenterology, 101, pp. 1701-1709, (1991)
[3]
Lee S.P., Nicholls J.F., Park H.Z., Biliary sludge as a cause of acute pancreatitis, N. Engl. J. Med., 326, pp. 589-593, (1992)
[4]
Kohut M., Nowak A., Nowakowska-Dulawa E., Et al., The frequency of bile duct crystals in patients with presumed biliary pancreatitis, Gastrointest. Endosc., 54, pp. 37-41, (2001)
[5]
Hogan W.J., Geenen J.E., Biliary dyskinesia, Endoscopy, 20, pp. 179-183, (1988)
[6]
Venu R.P., Geenen J.E., Hogan W., Et al., Idiopathic recurrent pancreatitis: An approach to diagnosis and treatment, Dig. Dis. Sci., 34, pp. 56-60, (1989)
[7]
Botoman V.A., Kozarek R.A., Novell L.A., Et al., Long-term outcome after endoscopic sphincterotomy in patients with biliary colic and suspected sphincter of Oddi dysfunction, Gastrointest. Endosc., 40, pp. 165-170, (1994)
[8]
Lee S.P., Nicholls J.F., Nature and composition of biliary sludge, Gastroenterology, 90, pp. 677-686, (1986)
[9]
Juniper K., Burson N., Biliary tract studies II. The significance of biliary crystals, Gastroenterology, 32, pp. 175-211, (1957)
[10]
Delchier J.C., Benfredj P., Preaux A.M., Et al., The usefulness of microscopic bile examination in patients with suspected microlithiasis: A prospective evaluation, Hepatology, 6, pp. 118-122, (1986)