Early epilepsy surgery

被引：17

作者：

Wiebe S. ^{[1
]}

机构：

[1] London Health Sciences Centre, London, Ont. N6A 5A5

来源：

Current Neurology and Neuroscience Reports | 2004年 / 4卷 / 4期

关键词：

Temporal Lobe Epilepsy; Focal Epilepsy; Hippocampal Atrophy; Seizure Freedom; Pharmacoresistant Epilepsy;

D O I：

10.1007/s11910-004-0058-9

中图分类号：

学科分类号：

摘要：

Uncontrolled epilepsy is associated with progressive cortical and hippocampal atrophy, substantial cognitive and psychosocial morbidity, and increased mortality. Seizure freedom is required to reverse such morbidity and mortality. Surgery is vastly superior to medical therapy for patients with chronic, refractory temporal lobe seizures, and is now the standard of care for these patients. On the other hand, the concept of early surgery requires further exploration and definition. Although there is no robust, direct evidence to support early epilepsy surgery, case series and cohort studies report an association between earlier surgery and better outcomes. The evidence for earlier epilepsy surgery is reviewed. Copyright © 2004 by Current Science Inc.

引用

页码：315 / 320

页数：5

共 46 条

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