Static and Dynamic Function of the Lower Esophageal Sphincter before and after Laparoscopic Nissen Fundoplication

被引:10
作者
Crookes P.F. [1 ]
Ritter M.P. [1 ]
Johnson W.E. [1 ]
Bremner C.G. [1 ]
Peters J.H. [1 ]
DeMeester T.R. [1 ,2 ]
机构
[1] Department of Surgery, Univ. of S. California Sch. of Med., Los Angeles, CA
[2] Department of Surgery, Univ. of S. California Sch. of Med., Los Angeles, CA 90033-4612
关键词
Lower Esophageal Sphincter; Residual Pressure; Lower Esophageal Sphincter Pressure; Esophageal Motility Disorder; Bolus Transit;
D O I
10.1016/S1091-255X(97)80064-9
中图分类号
学科分类号
摘要
The means by which fundoplication protects against reflux is disputed. We studied the resting and dynamic features of the lower esophageal sphincter (LES) and 24-hour pH monitoring in 26 patients before and after laparoscopic Nissen fundoplication. Resting features were LES pressure, abdominal length, and total length. Dynamic function was assessed by the residual pressure in the LES during a swallow measured as the bolus flowed though the LES. All patients experienced near-total relief of heartburn and all but one had normal postoperative acid scores. Resting LES characteristics were restored to normal. Mean residual pressure on swallowing was 7.1 ± 3.2 mm Hg in the patients postoperatively compared with 1.2 ± 1 mm Hg preoperatively and 4.0 ± 2.4 mm Hg in normal subjects. Eighteen of 26 patients had residual LES pressure within the normal range (<8.2 mm Hg). There was a tendency for residual pressures to be lower as experience with the procedure was gained. Incomplete LES relaxation is not necessary for effective functioning of a Nissen fundoplication. In construction of a Nissen fundoplication, creating a large retroesophageal window and deliberate dissection of the back of the posterior fundus from the left crus allows the creation of an effective antireflux procedure with restoration of static LES parameters to normal and minimal limitation of LES relaxation.
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页码:499 / 504
页数:5
相关论文
共 12 条
[1]  
Demeester T.R., Bonavina L., Albertucci M., Nissen fundoplication for gastroesophageal reflux diseases. Evaluation of primary repair in 100 consecutive patients, Ann Surg, 204, pp. 9-20, (1986)
[2]  
Johnsson J., Johnsson F., Joelsson B., Floren C.-H., Walther B., Outcome 5 years after 360° fundoplication for gastrooesophageal reflux disease, Br J Surg, 80, pp. 46-49, (1993)
[3]  
Ireland A.C., Holloway R.H., Toouli J., Dent J., Mechanisms underlying the antireflux action of fundoplication, Gut, 34, pp. 303-308, (1993)
[4]  
Peters J.H., Heimbucher J., Wkh K., Incarbone R., Bremner C.G., Demeester T.R., Clinical and physiologic comparison of laparoscopic and open Nissen fundoplication, J am Coll Surg, 180, pp. 385-393, (1995)
[5]  
Crookes P.F., Peters J.H., Demeester T.R., Physiology of the antireflux barrier and diagnostic tests of foregut function, Semin Laparosc Surg, 2, pp. 10-26, (1995)
[6]  
Kahrilas P.J., Dodds W.J., Hogan W.J., The effect of peristaltic dysfunction on esophageal volume clearance, Gastroenterology, 94, pp. 73-80, (1988)
[7]  
Demeester T.R., Wang C.-I., Wernly J.A., Pellegrini C.A., Little A.G., Klementschitch P., Bermudez G., Johnston L.F., Skinner D.B., Technique, indications, and clinical use of 24-hour pH monitoring, J Thorac Cardiovasc Surg, 79, pp. 656-670, (1980)
[8]  
Peters J.H., Demeester T.R., Technique of laparoscopic Nissen fundoplication, Semin Laparosc Surg, 2, pp. 27-44, (1995)
[9]  
Dent J., A new technique for continuous sphincter pressure measurement, Gastroenterology, 71, pp. 263-267, (1976)
[10]  
Castell J.A., Dalton C.B., Castell D.O., On-line computer analysis of human lower esophageal sphincter relaxation, Am J Physiol, 255, (1988)