Beneficial effects of Helicobacter pylori eradication on idiopathic chronic urticaria

被引：124

作者：

Di Campli C. ^{[1
]}

Gasbarrini A. ^{[1
,2
]}

Nucera E. ^{[1
]}

Franceschi F. ^{[1
]}

Ojetti V. ^{[1
]}

Torre E.S. ^{[1
]}

Schiavino D. ^{[1
]}

Pola P. ^{[1
]}

Patriarca G. ^{[1
]}

Gasbarrini G. ^{[1
]}

机构：

[1] Int. Med. and Allergology Service, Catholic University, Rome

[2] Istituto di Patologia Medica, Policlinico Gemelli, 00168 Rome

来源：

Digestive Diseases and Sciences | 1998年 / 43卷 / 6期

关键词：

H; pylori; Idiopathic chronic urticaria; Urea breath test;

D O I：

10.1023/A:1018851623109

中图分类号：

学科分类号：

摘要：

Helicobacter pylori, the most important cause of gastritis and peptic ulcer, recently has been associated with several extradigestive diseases. The aim of this study was to assess the prevalence of Helicobacter pylori infection and the effects of bacterium eradication in 42 consecutive patients affected by idiopathic chronic urticaria. Helicobacter pylori was assessed by [13C]urea breath test. Amoxicillin, clarithromycin, and lansoprazole were given to infected patients for seven days. Urticaria and gastrointestinal symptoms were assessed on enrollment and after eradication. Fifty-five percent of patients proved to be infected by Helicobacter pylori. Prevalence of gastrointestinal symptoms did not differ between infected and uninfected patients. Eighty-eight percent of infected patients in whom the bacterium was eradicated after therapy showed a total or partial remission of urticaria symptoms. Conversely, symptoms remained unchanged in all uninfected patients. In conclusion, Helicobacter pylori affects a high percentage of patients with idiopathic chronic urticaria; however, typical gastrointestinal symptoms do not identify infection status. Bacterium eradication is associated with a remission of urticaria symptoms, suggesting a possible role of Helicobacter pylori in the pathogenesis of this skin disorder.

引用

页码：1226 / 1229

页数：3

共 21 条

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