Anxiety, depression and quality of life in colorectal cancer patients

被引：98

作者：

Tsunoda A. ^{[1
]}

Nakao K. ^{[1
]}

Hiratsuka K. ^{[1
]}

Yasuda N. ^{[1
]}

Shibusawa M. ^{[1
]}

Kusano M. ^{[1
]}

机构：

[1] Second Department of Surgery, Showa University, School of Medicine, Shinagawa-ku, Tokyo 142-8666

来源：

International Journal of Clinical Oncology | 2005年 / 10卷 / 6期

关键词：

Colorectal cancer patients; EORTC QLQ-C30; HADS;

D O I：

10.1007/s10147-005-0524-7

中图分类号：

学科分类号：

摘要：

Background. Few studies have examined psychological distress and its relationship with quality of life (QL) dimensions in colorectal cancer patients. Methods. One hundred and twenty-eight outpatients were given psychological tests for anxiety and depression (Hospital Anxiety and Depression Scale; HADS) and QL The European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire C30 (EORTC QLQ-C30) on the same occasion. The association between the patients' emotional function (EF) scoring on EORTC QLQ-C30 and their HADS scores was analyzed by multiple linear regression. Results. Statistically significant negative relationships were found between EF and HADS-A (anxiety), HADS-D (depression), and HADS-T (total score), respectively, with the highest correlation coefficient being for HADS-A. However, HADS-D was significantly more highly correlated than HADS-A to other QL dimensions, and depression was more highly correlated than anxiety with reduced QL. Conclusion. The EF dimension of the EORTC QLQ-C30 predominantly assesses anxiety. Depression has a stronger impact on the global QL of patients than anxiety; therefore, the use of an additional instrument is recommended for the assessment of depression in outpatients with colorectal cancer. © The Japan Society of Clinical Oncology 2005.

引用

页码：411 / 417

页数：6

共 43 条

[1]

Derogatis L.R., Morrow G.R., Fetting J., Et al., The prevalence of psychiatric disorders among cancer patients, JAMA, 249, pp. 751-757, (1983)

[2]

Velikova G., Stark D., Selby P., Quality of life measurements in oncology, Eur J Cancer, 35, pp. 157-180, (1999)

[3]

Brown D.J., McMillan D.C., Milroy R., The correlation between fatigue, physical function, the systemic inflammatory response, and psychological distress in patients with advanced lung cancer, Cancer, 15, pp. 377-382, (2005)

[4]

Zigmord A.S., Snaith R.P., The Hospital Anxiety and Depression Scale, Acta Psychiatr Scand, 67, pp. 361-370, (1983)

[5]

Razavi D., Delvaux N., Farvacques C., Et al., Screening for adjustment disorder and major depressive disorders in cancer in-patients, Br J Psychiatry, 156, pp. 79-83, (1990)

[6]

Moorey S., Greer S., Watson M., Et al., The factor structure and factor stability of the hospital anxiety and depression scale in patients with cancer, Br J Psychiatry, 158, pp. 255-259, (1991)

[7]

Kugaya A., Akechi T., Okuyama T., Et al., Screening for psychological distress in Japanese cancer patients, Jpn J Clin Oncol, 28, pp. 333-338, (1998)

[8]

Aass N., Fossa S.D., Dahl A.A., Et al., Prevalence of anxiety and depression in cancer patients seen at the Norwegian Radium Hospital, Eur J Cancer, 33, pp. 1597-1604, (1997)

[9]

Aaronson N.K., Ahmedzai S., Bergman B., Et al., The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology, J Natl Cancer Inst, 85, pp. 365-376, (1993)

[10]

Kobayashi K., Takeda F., Teramukai S., Et al., A cross-validation of the European Organization for Research and Treatment of Cancer QLQ-C30 (EORTC QLQ-C30) for Japanese with lung cancer, Eur J Cancer, 34, pp. 810-815, (1998)

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