Late-phase urticaria update

被引:3
作者
Kambe N. [1 ]
Kitao A. [1 ]
Nishigori C. [1 ]
Miyachi Y. [1 ]
机构
[1] Department of Dermatology, Kyoto University Graduate School of Medicine, 54 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto
关键词
Activate Mast Cell; Chronic Urticaria; Dermatol; Urticaria; Urticarial Vasculitis;
D O I
10.1007/s11882-002-0052-8
中图分类号
学科分类号
摘要
In ordinary urticaria, individual lesions disappear within 24 hours. However, we sometimes encounter patients whose eruptions last longer than 24 hours, but without evidence of vasculitis or a history of exposure to pressure. In these patients, histology reveals a perivascular infiltration, predominantly of eosinophils, depending on the timing of the biopsy. Unlike urticarial vasculitis, no immunoglobulins, complement deposition, or endothelial fibrinoid degeneration is observed. The peripheral eosinophil counts and serum complement levels appear within normal range. No protein urea or joint pain is observed, and the lesions can be controlled only by systemic glucocorticoids. We recognize such a urticarial reaction as a different clinical entity than usual urticaria, which is presumably mediated by latephase inflammatory reaction in immediate hypersensitivity. © 2002, Current Science Inc.
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页码:288 / 291
页数:3
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