Incomplete functional recovery after delirium in elderly people: A prospective cohort study

被引:54
作者
Andrew M.K. [1 ]
Freter S.H. [1 ]
Rockwood K. [1 ]
机构
[1] Division of Geriatric Medicine, Dalhousie University, Halifax, NS
关键词
Dementia; Usual Care; Hospital Discharge; Functional Decline; Barthel Index;
D O I
10.1186/1471-2318-5-5
中图分类号
学科分类号
摘要
Background: Delirium often has a poor outcome, but why some people have incomplete recovery is not well understood. Our objective was to identify factors associated with short-term (by discharge) and long-term (by 6 month) incomplete recovery of function following delirium. Methods: In a prospective cohort study of elderly patients with delirium seen by geriatric medicine services, function was assessed at baseline, at hospital discharge and at six months. Results: Of 77 patients, vital and functional status at 6 months was known for 71, of whom 21 (30%) had died. Incomplete functional recovery, defined as ≥10 point decline in the Barthel Index, compared to pre-morbid status, was present in 27 (54%) of the 50 survivors. Factors associated with death or loss of function at hospital discharge were frailty, absence of agitation (hypoactive delirium), a cardiac cause and poor recognition of delirium by the treating service. Frailty, causes other than medications, and poor recognition of delirium by the treating service were associated with death or poor functional recovery at 6 months. Conclusion: Pre-existing frailty, cardiac cause of delirium, and poor early recognition by treating physicians are associated with worse outcomes. Many physicians view the adverse outcomes of delirium as intractable. While in some measure this might be true, more skilled care is a potential remedy within their grasp. © 2005 Andrew et al; licensee BioMed Central Ltd.
引用
收藏
相关论文
共 40 条
[1]  
McCusker J., Cole M., Dendukuri N., Belzile E., Primeau F., Delirium in older medical inpatients and subsequent cognitive and functional status: A prospective study, CMAJ, 165, pp. 575-583, (2001)
[2]  
McCusker J., Cole M., Abrahamowicz M., Primeau F., Belzile E., Delirium predicts 12-month mortality, Arch Intern Med, 162, pp. 457-463, (2002)
[3]  
Inouye S.K., Rushing J.T., Foreman M.D., Palmer R.M., Pompei P., Does delirium contribute to poor hospital outcomes? A three-site epidemiologic study, J Gen Intern Med, 13, pp. 234-242, (1998)
[4]  
Rahkonen T., Eloniemi-Sulkava U., Halonen P., Verkkoniemi A., Niinisto L., Notkola I.L., Sulkava R., Delirium in the non-demented oldest old in the general population: Risk factors and prognosis, Int J Geriatr Psychiatry, 16, pp. 415-421, (2001)
[5]  
Curyto K.J., Johnson J., TenHave T., Mossey J., Knott K., Katz I.R., Survival of hospitalized elderly patients with delirium: A prospective study, Am J Geriatr Psychiatry, 9, pp. 141-147, (2001)
[6]  
O'Keeffe S., Lavan J., The prognostic significance of delirium in older hospital patients, J Am Geriatr Soc, 45, pp. 174-178, (1997)
[7]  
Marcantonio E.R., Flacker J.M., Michaels M., Resnick N.M., Delirium is independently associated with poor functional recovery after hip fracture, J Am Geriatr Soc, 48, pp. 618-624, (2000)
[8]  
Lindesay J., Rockwood K., Rolfson D., The epidemiology of delirium, Delirium in Old Age, pp. 27-40, (2002)
[9]  
Britton A., Russell R., Multidisciplinary team interventions for delirium in patients with chronic cognitive impairment, Cochrane Database Syst Rev, (2001)
[10]  
Marcantonio E.R., Simon S.E., Bergmann M.A., Jones R.N., Murphy K.M., Morris J.N., Delirium symptoms in post-acute care: Prevalent, persistent, and associated with poor functional recovery, J Am Geriatr Soc, 51, pp. 4-9, (2003)