Cytochrome P450 oxygenases of monoterpene metabolism

被引：19

作者：

Mau C.J.D. ^{[1
]}

Croteau R. ^{[1
]}

机构：

[1] Institute of Biological Chemistry, Washington State University, Pullman, WA 99164-6340

来源：

Phytochemistry Reviews | 2006年 / 5卷 / 2-3期

关键词：

Hydroxylase; Lamiaceae;

D O I：

10.1007/s11101-006-9008-2

中图分类号：

学科分类号：

摘要：

The cytochrome P450 monoterpene oxygenases are largely responsible for imparting structural and functional diversity to this family of natural products. In most cases, cytochrome P450-mediated allylic hydroxylation of a parental monoterpene olefin leads to a series of redox transformations and conjugation reactions which yield a family of structurally related derivatives and isomers. An overview is provided of the extant monoterpene oxygenases, with examples mainly from the mint (Lamiaceae) family of essential oil plants, and, where possible, information on the structure, mechanism, localization and regulation of these enzymes is described. The review concludes with a brief assessment of biotechnological applications and a view to future research in this area. © 2006 Springer Science+Business Media B.V.

引用

页码：373 / 383

页数：10

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