Current Drug Therapy of Protozoal Diarrhoea

被引:21
作者
Gupta Y.K. [1 ,4 ]
Gupta M. [2 ]
Aneja S. [3 ]
Kohli K. [2 ]
机构
[1] Indust. Taxocology Res. Ctr. (ITRC), Lucknow
[2] Department of Pharmacology, Lady Hardinge Medical College, New Delhi
[3] Department of Pediatrics, Kalawati Saran Children's Hospital, Lady Hardinge Medical College, New Delhi
[4] Indust. Taxocology Res. Ctr. (ITRC), Lucknow - 226001, MG Marg
关键词
Amoebiasis; Diarrhoea; Giardiasis; Metronidazole; Protozoa; Tinidazole;
D O I
10.1007/BF02725657
中图分类号
学科分类号
摘要
Protozoal infections of the gastrointestinal tract occur worldwide and have substantial morbidity and mortality. Prevalence is higher in the economically deprived regions of the world, especially the developing countries. Infections like amoebiasis and giardiasis have a worldwide distribution, being endemic in India. Apart from producing GI symptoms, growth and development of children is also impaired. It is seen that protozoa multiply rapidly in their hosts and as there is a lack of effective vaccines, chemotherapy has been the only practiced way to treat individuals and reduce transmission. The current treatment modalities for protozoal diarrhoea include 5-nitrosoimidazoles, iodoquinol, diloxanide furoate, paromomycin, chloroquine, and trimethoprim-sulphamethoxazole.
引用
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页码:55 / 58
页数:3
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