Rare benign tumors of the liver: Still rare?

被引:14
作者
Bertino G. [1 ]
Ardiri A. [1 ]
Demma S. [1 ]
GiuseppeCalvagno S. [1 ]
Toro A. [2 ]
Basile E. [1 ]
Campagna D. [1 ]
Ferraro G. [1 ]
Frazzetto E. [1 ]
Proiti M. [1 ]
Malaguarnera G. [3 ]
Bertino N. [4 ]
Malaguarnera M. [3 ]
Malaguarnera M. [3 ]
Amaradio M.D. [1 ]
Pricoco G. [1 ]
Di Carlo I. [2 ]
机构
[1] Hepatology Unit, Department of Medical and Pediatric Science, University of Catania, 95123 Catania
[2] Department of Surgical Sciences, Organ Transplantation and Advanced Technologies, University of Catania, Catania
[3] Research Centre The Great Senescence, University of Catania, Catania
[4] Faculty of Pharmacy, University of Catania, Catania
关键词
Biliary cystadenoma; Hepatic angiomyolipoma; Hepatic benign tumors; Hepatic cystic tumors; Hepatic mesenchymal hamartoma; Liver macro-regenerative nodules; Nodular regenerative hyperplasia; Polycystic liver disease;
D O I
10.1007/s12029-014-9580-4
中图分类号
学科分类号
摘要
Background: Benign liver tumors are common. They do not spread to other areas of the body, and they usually do not pose a serious health risk. In fact, in most cases, benign liver tumors are not diagnosed because patients are asymptomatic. When they are detected, it's usually because the person has had medical imaging tests, such as an ultrasound (US), computed tomography (CT) scan, or magnetic resonance imaging (MRI), for another condition. Materials and methods: A search of the literature was made using cancer literature and the PubMed, Scopus, and Web of Science (WOS) database for the following keywords: "hepatic benign tumors", "hepatic cystic tumors", "polycystic liver disease", "liver macroregenerative nodules", "hepatic mesenchymal hamartoma", "hepatic angiomyolipoma", "biliary cystadenoma", and "nodular regenerative hyperplasia". Discussion and conclusion: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in some areas of the world; there is an increasing incidence worldwide. Approximately 750,000 new cases are reported per year. More than 75 % of cases occur in the Asia-Pacific region, largely in association with chronic hepatitis B virus (HBV) infection. The incidence of HCC is increasing in the USA and Europe because of the increased incidence of hepatitis C virus (HCV) infection. Unlike the liver HCC, benign tumors are less frequent. However, they represent a chapter always more interesting of liver disease. In fact, a careful differential diagnosis with the forms of malignant tumor is often required in such a way so as to direct the patient to the correct therapy. In conclusion, many of these tumors present with typical features in various imaging studies. On occasions, biopsies are required, and/or surgical removal is needed. In the majority of cases of benign hepatic tumors, no treatment is indicated. The main indication for treatment is the presence of significant clinical symptoms or suspicion of malignancy or fear of malignant transformation. © 2014 Springer Science+Business Media.
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页码:202 / 217
页数:15
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