Comparison of two composite meshes using two fixation devices in a porcine laparoscopic ventral hernia repair model

被引:45
作者
Duffy A.J. [1 ]
Hogle N.J. [1 ]
LaPerle K.M. [1 ]
Fowler D.L. [1 ,2 ]
机构
[1] Minimal Access Surgery Center, Department of Surgery, Weill Medical Coll. of Cornell Univ., New York, NY
[2] Presbyterian Hospital, New York, NY 10032
关键词
Adhesions; Laparoscopy; Prosthesis implantation; Surgical mesh; Ventral hernia;
D O I
10.1007/s10029-004-0258-x
中图分类号
学科分类号
摘要
Introduction: Laparoscopic ventral hernia repair uses tacks to secure mesh. The mesh is designed to maximize tissue ingrowth while minimizing adhesions. We hypothesized: (1) a collagen-coated polyester mesh (PCO) will form fewer adhesions than an ePTFE-polypropylene composite (BC) and (2) absorbable tacks are equivalent to metal tacks. Methods: In a porci ne model of adhesion formation, three pieces of 10×15-cm mesh were placed on the anterior abdominal wall. PCO was secured with absorbable (PLA) or metal tacks (PT), BC with PT. At 28 days, adhesion formation, abdominal-wall adherence, and tissue ingrowth were analyzed. Results: PCO induced fewer adhesions (14.5% vs 53.4%, P=0.007). On an adhesion scale (0-5), BC scored 3.6 vs 1.75 for PCO (P<0.03). There was no difference in adhesion strength, tack adhesions, or abdominal-wall peel force. Histology showed equal ingrowth. Conclusions: PCO induces fewer adhesions than BC. There is no difference in the ingrowth of the two mesh types. The PLA achieves equivalent mesh incorporation to the PT. © Springer-Verlag 2004.
引用
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页码:358 / 364
页数:6
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