Knee osteoarthritis in women

被引:168
作者
Hame S.L. [1 ]
Alexander R.A. [1 ]
机构
[1] Division of Sports Medicine, Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095
关键词
Elderly; Gender; Knee; Osteoarthritis; Total knee arthroplasty; Treatment; Women;
D O I
10.1007/s12178-013-9164-0
中图分类号
学科分类号
摘要
Osteoarthritis is a disease that progresses over time and culminates in the destruction of articular cartilage and joints. Thus, with an increasing elderly population the treatment of knee osteoarthritis has become a major healthcare issue. It has been shown that women are more severely impacted by knee osteoarthritis. Differences in knee anatomy, kinematics, previous knee injury, and hormonal influences may play a role. Sex difference with respect to osteoarthritis presentation, treatment, and the allocation of resources also exists. In general, women present for treatment in more advanced stages of osteoarthritis and have more debilitating pain than their male counterparts. In addition, healthcare providers are more likely to recommend total joint arthroplasty for their male patients. Understanding how and why these gender differences occur is instrumental in formulating an inclusive strategy for combating osteoarthritis in the future. © 2013 Springer Science+Business Media New York.
引用
收藏
页码:182 / 187
页数:5
相关论文
共 52 条
[1]
Borkhoff C.M., Hawker G.A., Kreder H.J., Glazier R.H., Mahomed N.N., Wright J.G., The effect of patient's sex on physician's recommendations for total knee arthroplasty, CMAJ, 178, pp. 681-687, (2008)
[2]
Blagojevic M., Jinks C., Jeffery A., Jordan K.P., Risk factors for onset of osteoarthritis of the knee in elderly adults: A systematic review and meta-analysis, Osteoarthr Cartil, 18, pp. 24-33, (2010)
[3]
Felson D.T., Naimark A., Anderson J., Kazis L., Castelli W., Meenan R.F., The prevalence of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study, Arthritis Rheum, 30, pp. 914-918, (1987)
[4]
Felson D.T., Zhang Y., Hannan M.T., Naimack A., Weissman B.N., Aliabadi P., Et al., The incidence and natural history of knee osteoarthritis in the elderly. The Framingham Osteoarthritis Study, Arthritis Rheum, 38, pp. 1500-1505, (1995)
[5]
O'Connor M.I., Osteoarthritis of the hip and knee: Sex and gender differences, Orthop Clin N Am, 37, pp. 559-568, (2006)
[6]
Srikanth V.K., Fryer B., Math J.L., Zhai G., Winzenberg T.M., Hosmer D., Et al., A meta-analysis of sex differences prevalence, incidence, and severity of osteoarthritis, Osteoarthr Cartil, 13, pp. 769-781, (2005)
[7]
Hanna F.S., Teichtahl A.J., Wluka A.E., Wang Y., Urquhart D.M., English D.R., Et al., Women have increased rates of cartilage loss and progression of cartilage defects at the knee than men: A gender study of adults without clinical knee osteoarthritis, Menopause, 4, pp. 666-670, (2009)
[8]
McAlindon T.E., Cooper C., Kirwan J.R., Dieppe P.A., Knee pain and disability in the community, Br J Rheumatol, 31, pp. 189-192, (1992)
[9]
O'Connor M.I., Sex differences in osteoarthritis of the hip and knee, J Am Acad Orthop Surg, 15, (2007)
[10]
McAlindon T.E., Snow S., Cooper C., Dieppe P.A., Radiographic patterns of osteoarthritis of the knee joint in the community: The importance of the patellofemoral joint, Ann Rheum Dis, 51, pp. 844-849, (1992)