Applications of diffusion/perfusion magnetic resonance imaging in experimental and clinical aspects of stroke

被引:9
作者
Duong T.Q. [1 ]
Fisher M. [1 ]
机构
[1] Center for Comparative NeuroImaging, Univ. of Massachusetts Med. School, Worcester, MA 01655
关键词
Apparent Diffusion Coefficient; Cerebral Blood Flow; Acute Stroke; Magn Reson Image; Stroke Onset;
D O I
10.1007/s11883-004-0057-y
中图分类号
学科分类号
摘要
The acute evaluation of stroke patients has undergone dramatic advances in the recent past. The increasing availability of novel magnetic resonance imaging (MRI) techniques, such as diffusion and perfusion MRI, provides a plethora of information to clinicians evaluating patients suspected of having an acute stroke. This review focuses on recent advances with experimental and clinical applications of perfusion and diffusion imaging and their utility in identifying potentially salvageable ischemic tissue in rat stroke model and stroke patients. Copyright © 2004 by Current Science Inc.
引用
收藏
页码:267 / 273
页数:6
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共 44 条
[1]  
Moseley M.E., Cohen Y., Mintorovitch J., Et al., Early detection of regional cerebral ischemia in cats: Comparison of diffusion- and T2-weighted MRI and spectroscopy, Magn. Reson. Med., 14, pp. 330-346, (1990)
[2]  
Zhong J., Petroff A.C., Prichard J.W., Gore J.C., Changes in water diffusion and relaxation properties of rat cerebrum during status epilepticus, Magn. Reson. Med., 30, pp. 241-246, (1993)
[3]  
van der Toorn A., Dijkhuizen R.M., Tulleken C.A., Nicolay K., Diffusion of metabolites in normal and ischemic rat brain measured by localized 1H MRS, Magn. Reson. Med., 36, pp. 914-922, (1996)
[4]  
Duong T.Q., Ackerman J.J., Ying H.S., Neil J.J., Evaluation of extra- and intracellular apparent diffusion in normal and globally ischemic rat brain via 19F NMR, Magn. Reson. Med., 40, pp. 1-13, (1998)
[5]  
Silva M.D., Omae T., Helmer K.G., Et al., Separating changes in the intra- and extracellular water apparent diffusion coefficient following focal cerebral ischemia in the rat brain, Magn. Reson. Med., 48, pp. 826-837, (2002)
[6]  
Hossmann K.A., Viability thresholds and the penumbra of focal ischemia, Ann. Neurol., 36, pp. 557-565, (1994)
[7]  
Warach S., Dashe J., Edelman R., Clinical outcome in ischemic stroke predicted by early diffusio-weighted and perfusion magnetic resonance imaging, J. Cereb. Blood Flow Metab., 16, pp. 53-59, (1996)
[8]  
Helpern J.A., Dereski M.O., Knight R.A., Et al., Histopathological correlations of nuclear magnetic resonance imaging parameters in experimental cerebral ischemia, Magn. Reson. Imaging, 11, pp. 241-246, (1993)
[9]  
Albers G.W., Expanding the window for thrombolytic therapy in acute stroke: The potential role of acute MRI for patient selection, Stroke, 30, pp. 2230-2237, (1999)
[10]  
Calamante F., Thomas D.L., Pell G.S., Et al., Measuring cerebral blood flow using magnetic resonance imaging techniques, J. Cereb. Blood Flow Metab., 19, pp. 701-735, (1999)