Mycosis fungoides and Sezary Syndrome: An update

被引：15

作者：

Kim E.J. ^{[1
]}

Lin J. ^{[1
]}

Junkins-Hopkins J.M. ^{[1
]}

Vittorio C.C. ^{[1
]}

Rook A.H. ^{[1
]}

机构：

[1] Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104

来源：

Current Oncology Reports | 2006年 / 8卷 / 5期

关键词：

Dermatol; Mycosis Fungoides; Bexarotene; Sezary Syndrome; Denileukin Diftitox;

D O I：

10.1007/s11912-006-0061-1

中图分类号：

学科分类号：

摘要：

Mycosis fungoides (MF), and the associated leukemic variant Sezary Syndrome (SS), are the most common group of cutaneous T-cell lymphomas. MF/SS is a non-Hodgkin's lymphoma of mature, skin-homing, clonal, malignant T lymphocytes that initially presents in the skin as patches, plaques, tumors, or generalized erythema (erythroderma) and can involve the lymph nodes and peripheral blood. Much progress has been made in recent years in understanding the origin of the malignant T cell in MF/ SS and the pathophysiology and immunology of the disease. This recent work has made a great impact on diagnosis, prognostication, and treatment. In this review, we survey the MF/SS published literature over the past year and highlight some of the important advances. Copyright © 2006 by Current Science Inc.

引用

页码：376 / 386

页数：10

共 69 条

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