Human herpesvirus 8 infections

被引:5
作者
Ruth M. Greenblatt
机构
[1] University of California,Infectious Diseases Division
[2] San Francisco,undefined
关键词
Cidofovir; Foscarnet; Solid Organ Transplant Recipient; Lytic Antibody; Macrophage Inhibitory Protein;
D O I
10.1007/s11908-999-0031-5
中图分类号
学科分类号
摘要
Human herpesvirus 8 (HHV-8) or Kaposi’s sarcoma (KS)-associated herpesvirus is a recently identified virus that is associated with KS, multicentric Castleman’s disease, and body cavity-based lymphomas. KS is the most common kind of cancer in AIDS patients and the initial AIDS-defining condition in over 20% of patients. HHV-8 DNA has now been detected in over 95% of KS tissue samples supporting the concept that HHV-8 has a causal role in KS. The discovery has opened new avenues for understanding the epidemiology, pathogenesis, and treatment of KS and related conditions.
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页码:279 / 285
页数:6
相关论文
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