Early onset of ganciclovir-resistant cytomegalovirus infection in a lung-transplant recipient

被引:4
作者
Chen F. [1 ]
Bando T. [1 ,2 ]
Hanaoka N. [1 ]
Fukuse T. [1 ]
Hasegawa S. [1 ]
Wada H. [1 ]
机构
[1] Department of Thoracic Surgery, Kyoto University, Kyoto
[2] Department of Thoracic Surgery, Kyoto University, Sakyo-ku, Kyoto 606-8507
关键词
Cytomegalovirus; Foscarnet; Ganciclovir-resistant; Lung transplantation; Prophylaxis;
D O I
10.1007/s11748-005-0068-9
中图分类号
学科分类号
摘要
Ganciclovir resistance in cytomegalovirus (CMV) is an increasing problem in lung-transplant recipients with adverse clinical outcomes. We experienced the successful treatment of ganciclovir-resistant CMV infection in a lung-transplant recipient still receiving CMV prophylaxis. A 24-year-old woman with lymphangioleiomyomatosis underwent a living-donor lobar lung transplantation. She was a primary CMV mismatch (D+/R-) patient. She recovered from her postoperative complications, and was about to be discharged. However, she suffered ganciclovir-resistant CMV infection during prophylactic therapy. She was successfully treated with foscarnet, and is now alive without recurrence 18 months after surgery.
引用
收藏
页码:562 / 564
页数:2
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