Early onset of ganciclovir-resistant cytomegalovirus infection in a lung-transplant recipient

被引：4

作者：

Chen F. ^{[1
]}

Bando T. ^{[1
,2
]}

Hanaoka N. ^{[1
]}

Fukuse T. ^{[1
]}

Hasegawa S. ^{[1
]}

Wada H. ^{[1
]}

机构：

[1] Department of Thoracic Surgery, Kyoto University, Kyoto

[2] Department of Thoracic Surgery, Kyoto University, Sakyo-ku, Kyoto 606-8507

来源：

The Japanese Journal of Thoracic and Cardiovascular Surgery | 2005年 / 53卷 / 10期

关键词：

Cytomegalovirus; Foscarnet; Ganciclovir-resistant; Lung transplantation; Prophylaxis;

D O I：

10.1007/s11748-005-0068-9

中图分类号：

学科分类号：

摘要：

Ganciclovir resistance in cytomegalovirus (CMV) is an increasing problem in lung-transplant recipients with adverse clinical outcomes. We experienced the successful treatment of ganciclovir-resistant CMV infection in a lung-transplant recipient still receiving CMV prophylaxis. A 24-year-old woman with lymphangioleiomyomatosis underwent a living-donor lobar lung transplantation. She was a primary CMV mismatch (D+/R-) patient. She recovered from her postoperative complications, and was about to be discharged. However, she suffered ganciclovir-resistant CMV infection during prophylactic therapy. She was successfully treated with foscarnet, and is now alive without recurrence 18 months after surgery.

引用

页码：562 / 564

页数：2

共 10 条

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