Public health impact and cost-effectiveness of dairy products supplemented with vitamin D in prevention of osteoporotic fractures

被引：21

作者：

Ethgen O. ^{[1
]}

Hiligsmann M. ^{[2
]}

Burlet N. ^{[1
]}

Reginster J.-Y. ^{[1
]}

机构：

[1] Department of Public Health, Epidemiology and Health Economics, University of Liege, Liege

[2] Department of Health Services Research, Maastricht University, Maastricht

来源：

Archives of Public Health | / 73卷 / 1期

关键词：

Cost-effectiveness; Dairy products; Fracture; Osteoporosis; Vitamin D;

D O I：

10.1186/s13690-015-0099-3

中图分类号：

学科分类号：

摘要：

Background: Dietary sources of calcium and vitamin D are recommended as a first-line strategy in prevention of osteoporosis-related fractures but their public health and economic impact has never been studied. Methods: We designed a population-based model to forecast the potential health outcomes and medical effectiveness of the daily administration of dairy supplements containing 800 IU of vitamin D and 1 g of calcium in cohorts of subjects, from both genders, aged 50, 60, 70 and 80 years. Annual costs of dairy products were tested at €150, €250 and €350. Results: In total, the daily intake of vitamin-D rich dairy products reduces by 30,376 and 16,105 events the number of osteoporotic fractures in women and men respectively and permits to gain 6605 and 6144 life-years, in women and men respectively. This intervention is cost-effective from 70 years on in the general population and from 60 years on in patients at increased risk of osteoporotic fractures. Conclusion: The recommendation to use dairy products as the preferred source of calcium and vitamin D in aging males and females is supported by public health and health economic analyses. © 2015 Ethgen et al.

引用

共 57 条

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