Transformation of deoxynivalenol by the gut flora of pigs "in-vitro investigations on the adaptation dependent on the dosage form [Transformation von Deoxynivalenol durch die Darmflora des Schweines - In-vitro Untersuchungen zur Adaptation in Abhängigkeit von der Darreichungsform]

被引：7

作者：

Lauber U. ^{[1
]}

Dillenburger T. ^{[1
]}

Schollenberger M. ^{[1
]}

Müller H.M. ^{[1
]}

Drochner W. ^{[1
]}

机构：

[1] Institut für Tierernährung (450), Universität Hohenheim, 70599 Stuttgart

来源：

Mycotoxin Research | 2000年 / 16卷 / Suppl 2期

关键词：

D O I：

10.1007/BF02940028

中图分类号：

学科分类号：

摘要：

To examine the biotransformation of Deoxynivalenol (DON) by the normal gut flora of pigs (in reliance on toxin-source) an in-vitro system was established. Suspensions of rectum contents from different treated animals were incubated with pure DON. Despite fast adaptation of microflora (Deepoxidaton of DON) of animals fed wheat diet, no effects on reduced feed consumption and weight gain were seen. Even fast adaptation of microflora (lower intestine) couldn't avoid DON-effects in vivo.

引用

页码：166 / 169

页数：3

共 4 条

[1]

Lauber U., Dillenburger T., Schollenberger M., Muller H.M., Drochner W., Effects of feeding diets containing Deoxynivalenol (DON) of natural origin Fusarium contaminated wheat) and in pure form in growing pigs, Veröffentlichung in Vorbereitung, (2000)

[2]

Kollarczik B., Gareis M., Hanelt M., In vitro transformation of the Fusarium mycotoxins Deoxynivalenol and Zearalenon by the normal gut microflora of pigs, Nat. Tox., 2, pp. 105-110, (1994)

[3]

Schollenberger M., Lauber U., Terry H., Suchy S., Drochner W., Muller H.-M., Determination of eight trichothecenes by gas chromatography mass spectrometry after sample clean-up by a two-stage solid-phase extraction, J. Chrom., 815, pp. 123-132, (1998)

[4]

Hedman R., Toxikology of Nivalenol in Farm Animals, and Methods of its Production and Analysis, (1996)

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