Biofilms: A clinical perspective

被引:10
作者
Bell M. [1 ]
机构
[1] Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, National Center for Infectious Diseases, 1600 Clifton Road, A-35, Atlanta, 30333, GA
关键词
Contact Lens Storage Case; Lower Respiratory Tract Disease; Otitis Externa; Prosthetic Heart Valve; Vascular Access Device;
D O I
10.1007/s11908-001-0084-6
中图分类号
学科分类号
摘要
Biofilms play an increasingly recognized role in many aspects of human disease. Most of our understanding of infections is based on research that has examined free-living organisms. The results do not necessarily apply to biofilm organisms, since metabolic and synthetic characteristics of free-living organisms can change when they assume the biofilm mode of growth. Biofilms reduce our ability to eradicate infections, causing relapses after seemingly appropriate therapy. Awareness of biofilms, prevention of contamination of implanted or invasive devices, and use of appropriate antimicrobial dosing and treatment durations can limit the negative impact of biofilms while we strive for new technological solutions. © 2001, Current Science Inc.
引用
收藏
页码:483 / 486
页数:3
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