Human herpesvirus 6 infection of the central nervous system

被引：14

作者：

Caserta M.T. ^{[1
]}

机构：

[1] University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642

来源：

Current Infectious Disease Reports | 2004年 / 6卷 / 4期

关键词：

Multiple Sclerosis; Encephalitis; Temporal Lobe Epilepsy; Primary Infection; Febrile Seizure;

D O I：

10.1007/s11908-004-0054-x

中图分类号：

学科分类号：

摘要：

Human herpesvirus (HHV) 6 infects all children, usually during the first year of life. High fever is the hallmark of primary infection, with febrile seizures the most common complication. After primary infection, HHV-6 remains latent or persistent at multiple sites, with intermittent reactivation. Many disorders of the central nervous system (CNS) have been linked to HHV-6 reactivation, including chronic seizure disorders, encephalitis, and demyelinating disorders including multiple sclerosis. Although multiple studies have pieced together an understanding of the molecular organization, viral characteristics, immunology, and epidemiology of HHV-6, the true role of this virus in diseases of the CNS is still unfolding. Copyright © 2004 by Current Science Inc.

引用

页码：316 / 321

页数：5

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