A 12-hour urine collection accurately assesses proteinuria in the hospitalized hypertensive gravida

被引:11
作者
Rinehart B.K. [1 ,2 ]
Terrone D.A. [1 ]
Larmon J.E. [1 ]
Perry Jr. K.G. [1 ]
Martin R.W. [1 ]
Martin Jr. J.N. [1 ]
机构
[1] Division of Malernal-Fetal Medicine, Dept. of Obstetrics and Gynecology, Univ. of Mississippi Medical Center, Jackson, MS
[2] Dept. of Obstetrics and Gynecology, Univ. of Milississippi Med. Center, Jackson, MS 39216-4505
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D O I
10.1038/sj.jp.7200271
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摘要
OBJECTIVE: To determine whether a urine collection of <24 hours duration accu-rately assesses the level of proteinuria in inpatients being evaluated for preeclampsia. STUDY DESIGN: Patients admitted to the University of Mississippi between January and June of 1998 for evaluation of preeclampsia underwent two consecutive 12-hour urine collections. Each collection was analyzed for total protein, total calcium, total volume, and urine creatinine. A concurrent serum creatinine value was obtained. The protein:creatinine ratio, calcium: creatinine ratio, and creatinine clearance were calculated. Pearson's correlation, sensitivity, specificity, and positive and negative predictive values were assessed. RESULTS: A total of 25 patients (86%) were preeclamptic. Total protein, the protein: creatinine ratio, and serum creatinine were significantly correlated between the first and second urine collection. The sensitivity and specificity of the 12-hour urine collection was 96% and 100%, respectively. CONCLUSION: A 12-hour urine collection accurately depicts the amount of proteinuria in hospitalized gravidas being evaluated for preeclampsia.
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页码:556 / 558
页数:2
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