Effect of vitamin E on platelet enzymatic anti-oxidants in the patients of myocardial infarction

被引：7

作者：

Dwivedi V.K. ^{[1
]}

Chandra M. ^{[2
]}

Misra P.C. ^{[1
]}

Misra M.K. ^{[1
]}

机构：

[1] Department of Biochemistry, University of Lucknow

[2] C.S.M. Medical University, Lucknow

来源：

Indian Journal of Clinical Biochemistry | 2005年 / 20卷 / 1期

关键词：

Anti-oxidant enzymes; Lipid per oxidation; Myocardial infarction; Platelets; Vitamin E;

D O I：

10.1007/BF02893036

中图分类号：

学科分类号：

摘要：

Effect of administration of 600 mg. vitamin E each day, for six days, was observed on activity of some of the anti-oxidant enzymes and levels of malondialdehyde (as an index of free radical mediated damage) in the platelets of patients reperfused after myocardial infarction. It has been found that vitamin E administration significantly lowers the level of malondialdehyde in the patients. Vitamin E administration increases the activities of anti oxidant enzymes (viz. superoxide dismutase, glutathione reductase and catalase) tested both in the patients and healthy controls. Vitamin E administration causes general stimulation of anti-oxidant enzyme activities both in healthy persons and the patients, however, lowering of lipid per-oxidation upon administration of vitamin E is specific for patients. These findings exhibit beneficial role of vitamin E administration in the management of the patients reperfused after myocardial infarction.

引用

页码：21 / 25

页数：4

共 25 条

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