Sentinel lymphadenectomy in breast cancer: An alternative to routine axillary dissection

被引：9

作者：

Noguchi M. ^{[1
,2
]}

Kawahara F. ^{[2
]}

Tsugawa K. ^{[2
]}

Bando E. ^{[2
]}

Miwa K. ^{[2
]}

Yokoyama K. ^{[3
]}

Nakajima K.-I. ^{[3
]}

Tonami N. ^{[3
]}

机构：

[1] Operation Center, Kanazawa University Hospital, School of Medicine, Kanazawa 920, Takara-machi

[2] Department of Surgery II, Kanazawa University Hospital, School of Medicine

[3] Department of Nuclear Medicine, Kanazawa University Hospital, School of Medicine

来源：

Breast Cancer | 1998年 / 5卷 / 1期

关键词：

Axillary dissection; Breast cancer; Sentinel lymphadenectomy;

D O I：

10.1007/BF02967410

中图分类号：

学科分类号：

摘要：

We reviewed the literature concerning sentinel lymphadenectomy in breast cancer and reached the following conclusions: (a) A combination of lymphoscintigraphy and dye-guided and/or gamma probeguided techniques are superior to either technique alone for identifying the sentinel lymph node, (b) Immediate and reliable intraoperative information on the sentinel node is vital for the technique's success. However, the reliability of sentinel node diagnosis using frozen sections is questionable, because micrometastatic foci cannot be identified, (c) A reverse transcriptase-polymerase chain reaction (RT-PCR) method is more sensitive than immunohistochemistry for the detection of micrometastasis in the sentinel node, (d) Until there are new tumor markers or new imaging techniques to identify axillary metastasis without operative intervention, sentinel lymphadenectomy is a highly accurate, minimally invasive way to assess disease extent. Before sentinel lymphadenectomy gains general acceptance for patients with primary breast cancer, however, a large clinical trial will be essential to verify the value of this technology.

引用

页码：1 / 6

页数：5

共 52 条

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