The association between bone health indicated by calcaneal quantitative ultrasound and metabolic syndrome in Malaysian men

被引：6

作者：

Chin K.-Y. ^{[1
]}

Ima-Nirwana S. ^{[1
]}

Mohamed I.N. ^{[1
]}

Ahmad F. ^{[2
]}

Mohd Ramli E.S. ^{[2
]}

Aminuddin A. ^{[3
]}

Wan Ngah W.Z. ^{[4
]}

机构：

[1] Pharmacology Department, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak 56000 Cheras, Kuala Lumpur

[2] Anatomy Department, Universiti Kebangsaan Malaysia, Medical Centre, Kuala Lumpur

[3] Physiology Department, Universiti Kebangsaan Malaysia, Medical Centre, Kuala Lumpur

[4] Biochemistry Department, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur

来源：

Journal of Diabetes & Metabolic Disorders | / 14卷 / 1期

关键词：

Bone; Calcaneal; Men; Metabolic syndrome; Quantitative ultrasound;

D O I：

10.1186/s40200-015-0136-3

中图分类号：

学科分类号：

摘要：

Background: Previous studies on the relationship between bone health and metabolic syndrome (MS) have revealed heterogeneous results. There are limited studies employing bone quantitative ultrasonometry in evaluating this relationship. This study aimed to determine the relationship between MS and bone health in a group of Malaysian middle-aged and elderly men using bone quantitative ultrasonometry.Methods: This cross-sectional study recruited 309 free living Chinese and Malay men aged 40 years and above residing in Klang Valley, Malaysia. Their demographic and anthropometric data were collected. Their calcaneal speed of sound (SOS) was measured using a CM-200 bone ultrasonometer. Their blood was collected for the evaluation of lipid profile, total testosterone and sex hormone-binding globulin. The joint interim MS definition was used for the classification of subjects. Multiple linear regression analysis was used to assess the association between SOS and indicators of MS and the presence of MS, with suitable adjustment for confounders.Results: There was no significant difference in SOS value between MS and non-MS subjects (p > 0.05). The SOS values among subjects with different MS scores did not differ significantly (p > 0.05). There were no significant associations between SOS values and indicators of MS or the presence of MS (p > 0.05).Conclusions: The relationship between bone health and MS is not significant in Malaysian middle-aged and elderly men. A longitudinal study should be conducted to evaluate the association between bone loss and MS to confirm this finding. © 2015 Chin et al.

引用

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