Lowering the thyroid dose in screening examinations of the cervical spine

被引:22
作者
Shu K.M. [1 ]
MacKenzie J.D. [1 ]
Smith J.B. [1 ]
Blinder E.M. [1 ]
Bourgeois L.M. [1 ]
Ledbetter S. [1 ]
Castronovo F.P. [1 ]
Judy P.F. [1 ]
Rybicki F. [1 ,2 ]
机构
[1] Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston
[2] Department of Radiology, Boston, MA 02115
关键词
Cervical spine; CT; Radiation dosimetry;
D O I
10.1007/s10140-005-0462-8
中图分类号
学科分类号
摘要
The first objective of this study was to test the hypothesis that a lower-dose (14.1 mGy thyroid dose) protocol for helical computed tomography (CT) of the entire cervical spine demonstrates equivalent technical adequacy and diagnostic accuracy as the standard-dose protocol (26.0 mGy thyroid dose) used at our institution. The second objective was to estimate the excess thyroid cancer mortality for three cervical spine screening protocols. Eight patients underwent two helical CT acquisitions of the entire cervical spine (standard and lower dose); from these acquisitions, a database of 128 randomized images (64 standard dose and 64 lower dose) was constructed. Three radiologists evaluated each of the 128 images for technical adequacy and, if the image was technically adequate, diagnostic accuracy. Historical data of excess thyroid cancer mortality stratified by age and sex were used to estimate the impact of lowering the thyroid dose in cervical spine screening. Estimates used a linear extrapolation of mortality data. The lower-dose protocol for helical CT of the entire cervical spine demonstrates equivalent technical adequacy and diagnostic accuracy as the standard protocol. The excess thyroid cancer mortality is a function of patient age and sex; for 25-year-old men, the excess mortality per 100,000 patients is 96.7 (standard-dose CT), 52.4 (lower-dose CT), and 6.7 (radiographs alone, 1.8 mGy thyroid dose). The equivalent technical adequacy and diagnostic accuracy of a lower-dose protocol for helical CT of the entire cervical spine support its implementation in routine screening. The excess thyroid mortality emphasizes the need to maintain an open dialogue with our referring clinicians with respect to the mechanism of injury, clinical findings, and radiation risks. © Am Soc Emergency Radiol 2005.
引用
收藏
页码:133 / 136
页数:3
相关论文
共 20 条
[1]  
Nunez D.B., Ahmad A.A., Coin C.G., LeBlang S., Becerra J.L., Henry R., Clearing the cervical spine in multiple trauma victims: A time-effective protocol using helical computed tomography, Emerg Radiol, 1, pp. 273-278, (1994)
[2]  
Nunez Jr. D.B., Zuluaga A., Fuentes-Bernardo D.A., Rivas L.A., Becerra J.L., Cervical spine trauma: How much more do we learn by routinely using helical CT?, Radiographics, 16, pp. 1307-1318, (1996)
[3]  
Nunez Jr. D.B., Quencer R.M., The role of helical CT in the assessment of cervical spine injuries, AJR Am J Roentgenol, 171, pp. 951-957, (1998)
[4]  
Rybicki F.J., Knoll B., McKenney K., Zou K.H., Nunez D.B., Imaging of cervical spine trauma: Are the anteroposterior and odontoid radiographs needed when CT of the entire cervical spine is routine?, Emerg Radiol, 7, pp. 352-355, (2000)
[5]  
Ptak T., Kihiczak D., Lawrason J.N., Et al., Screening for cervical spine trauma with helical CT: Experience with 676 cases, Emerg Radiol, 8, pp. 315-319, (2001)
[6]  
Lawrason J.N., Novelline R.A., Rhea J.T., Sacknoff R., Kihiczak D., Ptak T., Can CT eliminate the initial portable lateral cervical spine radiograph hi the multiple trauma patient? a review of 200 cases, Emerg Radiol, 8, pp. 272-275, (2001)
[7]  
Blackmore C.C., Ramsey S.D., Mann F.A., Deyo R.A., Cervical spine screening with CT in trauma patients: A cost-effectiveness analysis, Radiology, 212, pp. 117-125, (1999)
[8]  
Hanson J.A., Blackmore C.C., Mann F.A., Wilson A.J., Cervical spine injury: A clinical decision rule to identify high-risk patients for helical CT screening, AJR Am J Roentgenol, 174, pp. 713-717, (2000)
[9]  
Rybicki F., Nawfel R.D., Judy P.F., Et al., Skin and thyroid dosimetry in cervical spine screening: Two methods for evaluation and a comparison between a helical CT and radiographic trauma series, AJR Am J Roentgenol, 179, pp. 933-937, (2002)
[10]  
Induction of Thyroid Cancer by Ionizing Radiation (Report No. 80), (1985)