Cellular composition of the piriform cortex of the rat brain in experimental epilepsy

被引：4

作者：

Bolkvadze T. ^{[1
]}

Dzhaparidze N.D. ^{[1
]}

Zhvaniya M.G. ^{[1
]}

Kotariya N.T. ^{[1
]}

Tsitsishvili A.Sh. ^{[1
]}

机构：

[1] Chemical Neuroanatomy Group, I. S. Beritashvili Institute of Physiology, Georgian Academy of Sciences, Tbilisi

来源：

Neuroscience and Behavioral Physiology | 2006年 / 36卷 / 3期

关键词：

Cellular composition; Experimental epilepsy; Piriform cortex; Rat;

D O I：

10.1007/s11055-006-0010-3

中图分类号：

学科分类号：

摘要：

The cellular composition of all layers of the anterior, central, and posterior parts of the piriform cortex of the rat brain was studied two weeks and one month after specific electrical stimulation (kindling) of the ventral hippocampus. Stereomicroscopic analysis at both two weeks and one month after kindling showed significant decreases in the numbers of pyramidal cells and interneurons in all layers of all parts of the piriform cortex. At two weeks, the numbers of pyramidal cells and interneurons in the central part of the piriform cortex also decreased in rats in which electrodes were inserted into the ventral hippocampus but without stimulation. These results, along with published data, led to a series of suggestions regarding the involvement of the piriform cortex in epileptogenesis. © 2006 Springer Science+Business Media, Inc.

引用

页码：271 / 274

页数：3

共 15 条

[1] Datiche F., Cattarelli M., Catecholamine innervation of the piriform cortex: A tracing and immunohistochemical study in the rat, Brain Res., 710, pp. 69-78, (1996)
[2] Datiche F., Litaudon P., Cattarelli M., Intrinsic association fiber system of the piriform cortex: A quantitative study based on a cholera toxin B subunit tracing in the rat, J. Comp. Neurol., 376, pp. 265-277, (1996)
[3] Ebert U., Wlaz R., Loscher W., High susceptibility of the anterior and posterior piriform cortex to induction of convulsions by bicuculline, Eur. J. Neurosci., 12, pp. 4195-4231, (2000)
[4] Ekstrand J.J., Domroease M.E., Johnson D.M., Et al., New subdivision of anterior piriform cortex and associate deep nucleus with novel features of interest for olfaction and epilepsy, J. Comp. Neurol., 434, 3, pp. 289-307, (2001)
[5] Haberly I.B., Olfactory cortex, The Synaptic Organization of the Brain, pp. 377-416, (1998)
[6] Johnston B.A., Leon M., Modular representations of odorants in the glomerular layer of the rat olfactory bulb and the effects of stimulus concentration, J. Comp. Neurol., 422, pp. 496-509, (2000)
[7] Kelly M.E., Staines W.A., McIntyre D.C., Secondary generalization of hippocampal kindled seizures in examining the role of the piriform cortex, Brain Res., 957, 1, pp. 152-161, (2002)
[8] Lehmann H., Ebert U., Loscher W., Amygdala-kindling induced a lasting reduction of GABA-immunoreactive neurons in a discrete area of the ipsilateral piriform cortex, Synapse, 29, 4, pp. 299-309, (1998)
[9] Loscher W., Ebert U., The role of piriform cortex in kindling, Progr. Neurobiol., 50, 5-6, pp. 427-481, (1996)
[10] Loscher W., Honack D., Gramer M., Effect of depth of electrode implantation with or without subsequent kindling on GABA turnover in various brain regions, Epilepsy Res., 37, 2, pp. 95-108, (1999)

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