Clinical characteristics of emergency department heart failure patients initially diagnosed as non-heart failure

被引:14
作者
Collins S.P. [1 ]
Lindsell C.J. [1 ]
Peacock W.F. [2 ]
Eckert D.C. [3 ]
Askew J. [3 ]
Storrow A.B. [4 ]
机构
[1] Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH
[2] Department of Emergency Medicine, The Cleveland Clinic, Cleveland, OH
[3] Department of Internal Medicine, Division of Cardiology, University of Cincinnati, Cincinnati, OH
[4] Department of Emergency Medicine, Vanderbilt University, Nashville, TN
关键词
Emergency Department; Heart Failure Patient; Decompensated Heart Failure; Emergency Department Patient; Emergency Department Physician;
D O I
10.1186/1471-227X-6-11
中图分类号
学科分类号
摘要
Background: Since previous studies suggest the emergency department (ED) misdiagnosis rate of heart failure is 10-20% we sought to describe the characteristics of ED patients misdiagnosed as non-decompensated heart failure in the ED. Methods: We analyzed a prospective convenience sample of 439 patients at 4 emergency departments who presented with signs or symptoms of decompensated heart failure. Patients with a cardiology criterion standard diagnosis of decompensated heart failure and an ED diagnosis of decompensated heart failure were compared to patients with a criterion standard of decompensated heart failure but no ED diagnosis of decompensated heart failure. Two senior cardiology fellows retrospectively determined the patient's heart failure status during their acute ED presentation. The Mann-Whitney u-test for two groups, the Kruskall-Wallis test for multiple groups, or Chi-square tests, were used as appropriate. Results: There were 173 (39.4%) patients with a criterion standard diagnosis of decompensated heart failure. Among those with this criterion standard diagnosis of decompensated heart failure, discordant patients without an ED diagnosis of decompensated heart failure (n = 58) were more likely to have a history of COPD (p =0.017), less likely to have a previous history of heart failure (p = 0.014), and less likely to have an elevated b-type natriuretic peptide (BNP) level (median 518 vs 764 pg/ml; p = 0.038) than those who were given a concordant ED diagnosis of decompensated heart failure. BNP levels were higher in those with a criterion standard diagnosis of decompensated heart failure than in those without a criterion standard diagnosis (median 657 vs 62.7 pg/ml). However, 34.6% of patients with decompensated heart failure had BNP levels in the normal (<100 pg/ml; 6.1%) or indeterminate range (100-500 pg/ml; 28.5%.). Conclusion: We found the ED diagnoses of decompensated heart failure to be discordant with the criterion standard in 14.3% of patients, the vast majority of which were due to a failure to diagnose heart failure when it was present. Patients with a previous history of COPD, without a previous history of heart failure and with lower BNP levels were more likely to have an ED misdiagnosis of non-decompensated heart failure. Readily available, accurate, objective ED tests are needed to improve the early diagnosis of decompensated heart failure in ED patients. © 2006 Collins et al; licensee BioMed Central Ltd.
引用
收藏
相关论文
共 15 条
[1]  
Dao Q., Krishnaswamy P., Kazanegra R., Et al., Utility of B-type natriuretic peptide in the diagnosis of congestive heart failure in an urgent-care setting, J Am Coll Cardiol, 37, 2, pp. 379-385, (2001)
[2]  
Collins S., Lindsell C.J., Storrow A.B., Abraham W.T., Prevalence of Negative Chest Radiography in the Emergency Department Patient with Decompensated Heart Failure, Ann Emerg Med, 47, 1, pp. 13-18, (2006)
[3]  
Collins S., Peacock W.F., Et al., The Effect of Treatment on the Presence of Abnormal Heart Sounds in Emergency Department Patients with Heart Failure, Am J Emerg Med, 24, 1, pp. 25-32, (2006)
[4]  
Collins S.P., Lindsell C.J., Peacock W.F., Et al., The combined utility of an S3 heart sound and B-type natriuretic peptide levels in emergency department patients with dyspnea, J Card Fail, 12, 4, pp. 286-292, (2006)
[5]  
(2003)
[6]  
Marcus G.M., Gerber I.L., McKeown B.H., Et al., Association between phonocardiographic third and fourth heart sounds and objective measures of left ventricular function, Jama, 293, 18, pp. 2238-2244, (2005)
[7]  
Peacock IV W.F., Fonarow G.C., Emerman C.L., Mills R.M., Wynne J., Impact of Early Initiation of Intravenous Therapy for Acute Decompensated Heart Failure on Outcomes in ADHERE, Cardiology, 107, 1, pp. 44-51, (2006)
[8]  
Maisel A.S., Krishnaswamy P., Nowak R.M., Et al., Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure, N Engl J Med, 347, 3, pp. 161-167, (2002)
[9]  
Collins S.P., Lindsell C.J., Peacock W.F., Hedger V.D., Storrow A.B., The Effect of Treatment on the Presence of Abnormal Heart Sounds in Emergency Department Patients with Heart Failure, American Journal of Emergency Medicine, (2005)
[10]  
Wang C.S., FitzGerald J.M., Schulzer M., Mak E., Ayas N.T., Does this dyspneic patient in the emergency department have congestive heart failure?, Jama, 294, 15, pp. 1944-1956, (2005)