The Applications of BioMEMS in Diagnosis, Cell Biology, and Therapy: A Review

被引：21

作者：

Menon K. ^{[1
]}

Joy R.A. ^{[1
]}

Sood N. ^{[1
]}

Mittal R.K. ^{[2
]}

机构：

[1] Department of Biotechnology, Birla Institute of Technology and Science, Pilani-Dubai Campus, Dubai

[2] Department of Mechanical Engineering, Birla Institute of Technology and Science, Pilani-Dubai Campus, Dubai

来源：

BioNanoScience | 2013年 / 3卷 / 04期

关键词：

Applications; BioMEMS; Cell-Sorting; Diagnosis; Microdevices; Therapy;

D O I：

10.1007/s12668-013-0112-7

中图分类号：

学科分类号：

摘要：

Bio-microelectromechanical systems (BioMEMS) have myriad applications that range from surgical tools to gene-sequencing chips. A full review of all its applications is beyond the scope of the present paper. This study is a comprehensive overview of applications of BioMEMS in the diagnosis of diseases, scientific research based on cell biology, and therapy or treatment of medical conditions. This is a review, from a biologist's perspective, of the current foci of research in these areas. The design and working principles applied are described, and progress made thus far is traced. Some of the design concepts that are likely to play an important role in future applications are also identified. Additionally, the major challenges to be overcome in order for BioMEMS technology to meet its full potential have been described. © 2013 Springer Science+Business Media New York.

引用

页码：356 / 366

页数：10

共 112 条

[1]

Ni M., Tong W.H., Choudhury D., Rahim N.A.A., Iliescu C., Yu H., Cell culture on MEMS platforms: a review, International Journal of Molecular Sciences, 10, pp. 5411-5441, (2009)

[2]

Jinseok H., Susan Z., An overview of recent strategies in pathogen sensing, Sensors, 9, pp. 4483-4502, (2009)

[3]

Raiteri R., Grattarola M., Butt H., Skladal P., Micromechanical cantilever-based biosensors, Sensors and Actuators B, 4010, pp. 1-12, (2001)

[4]

Shekhawat G., Tark S.H., Dravid V.P., MOSFET-embedded microcantilevers for measuring deflection in biomolecular sensors, Science, 311, 5767, pp. 1592-1595, (2006)

[5]

Wavering T.A., Meller S.A., Evans M.K., Pennington C., Jones M.E., Tassell R.V., Et al., Interferometric Optical Fiber Microcantilever Beam Biosensor, (2000)

[6]

Ji H.F., Gao H., Buchapudi K.R., Yang X., Xua X., Schulte M.K., Microcantilever biosensors based on conformational change of proteins, The Analyst, 133, pp. 434-443, (2008)

[7]

Kim E.S., Acoustic MEMS Transducers for Biomedical Applications, (2010)

[8]

de la Rica R., Mendoza E., Lechuga L.M., Matsui H., Label-free pathogen detection with sensor chips assembled from peptide nanotubes, Angewandte Chemie International Edition, 47, pp. 9752-9755, (2008)

[9]

Suehiro J., Ikeda N., Ohtsubo A., Imasaka K., Fabrication of bio/nano interfaces between biological cells and carbon nanotubes using dielectrophoresis, Microfluidics and Nanofluidics, 5, pp. 741-747, (2008)

[10]

Patolsky F., Zheng G., Lieber C.M., Nanowire-based biosensors, Analytical Chemistry, 78, 13, pp. 4260-4269, (2006)

← 1 2 3 4 5 6 7 8 9 10 →