Vascular smooth muscle diversity: Insights from developmental biology

被引:28
作者
Mark W. Majesky
机构
[1] Department of Pathology, Baylor College of Medicine, Houston, TX 77030, One Baylor Plaza
关键词
Neural Crest; Vascular SMCs; Cardiac Neural Crest; Smooth Muscle Marker; Aortic Arch Artery;
D O I
10.1007/s11883-003-0026-x
中图分类号
学科分类号
摘要
Vascular smooth muscle exhibits remarkable structural and functional diversity. For many years, this diversity was thought to be due to plasticity of a single type of smooth muscle cell responding to biologic and mechanical variations in the local environment However, recent studies of vascular development employing novel lineage mapping and mouse mutagenesis approaches suggest that much of the smooth muscle diversity found in adult blood vessels may have a developmental basis. Copyright © 2003 by Current Science Inc.
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页码:208 / 213
页数:5
相关论文
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