Recent advances in the treatment of opiate addiction

被引:18
作者
Fudala P.J. [1 ]
Woody G.W. [1 ]
机构
[1] Behavioral Health Service 116, Veterans Affairs Medical Center, Philadelphia, PA 19104, University and Woodland Avenues
关键词
Naloxone; Heroin; Personality Disorder; Buprenorphine; Harm Reduction;
D O I
10.1007/s11920-004-0020-1
中图分类号
学科分类号
摘要
Although addiction to heroin and other opiates is a major public health issue in the United States and many other counVies, advances in pharmacologic and nonpharmacologic treatment have been made. Some of these advances represent a major shift from traditional treatment philosophies, whereas others are characterized by more subtle, though important, improvements. This review discusses recent advances in opiate-addiction treatment in the context of three main domains: the use of buprenorphine and buprenorphine/naloxone in an office-based paradigm, psychosocial treatment and the addressing of medical and psychiatric comorbidity, and harm reduction strategy. Copyright © 2004 by Current Science Inc.
引用
收藏
页码:339 / 346
页数:7
相关论文
共 57 条
[1]  
(1916)
[2]  
(1919)
[3]  
(1974)
[4]  
(1974)
[5]  
Jaffe J.H., O'Keeffe C.O., From morphine clinics to buprenorphine: Regulating opioid agonist treatment of addiction in the United States, Drug Alcohol Depend, 70, SUPPL., (2003)
[6]  
Heel R.C., Brogden R.N., Speight T.M., Avery G.S., Buprenorphine: A review of its pharmacological properties and therapeutic efficacy, Drugs, 17, pp. 81-110, (1979)
[7]  
Jasinski D.R., Pevnick J.S., Griffith J.D., Human pharmacology and abuse potential of the analgesic buprenorphine: A potential agent for treating narcotic addiction, Arch. Gen. Psychiatry, 35, pp. 501-516, (1978)
[8]  
Martin W.R., Eades C.G., Thompson J.A., Et al., The effects of morphine- and nalorphine-like drugs in the nondependent and morphine-dependent chronic spinal dog, J. Pharmacol. Exp. Ther., 197, pp. 517-532, (1976)
[9]  
Villiger J.W., Taylor K.M., Buprenorphine: Characteristics of binding sites in the rat central nervous system, Life Sci., 29, pp. 2699-2708, (1981)
[10]  
Sadee W., Richards M.L., Grevel J., Rosenbaum J.S., In vivo characterization of four types of opioid binding sites in rat brain, Life Sci., 33, pp. 187-189, (1983)