Pathophysiology of obesity hypertension

被引：118

作者：

Hall J.E. ^{[1
]}

机构：

[1] Department of Physiology and Biophysics, University of Mississippi, Medical Center, Jackson, MS 39216-4505

来源：

Current Hypertension Reports | 2000年 / 2卷 / 2期

关键词：

Brown Adipose Tissue; Sympathetic Activity; Sodium Reabsorption; Obese Person; Excess Weight Gain;

D O I：

10.1007/s11906-000-0073-4

中图分类号：

学科分类号：

摘要：

Excess weight gain is a major cause of essential hypertension, and abnormal kidney function appears to be a cause as well as a consequence of obesity hypertension. Excess renal sodium reabsorption and a hypertensive shift of pressure natriuresis play a major role in mediating increased blood pressure associated with weight gain. Activation of the renin-angiotensin and sympathetic nervous systems and physical compression of the kidneys appear to contribute to obesity-induced increases in sodium reabsorption and hypertension. Copyright © 2000 by Current Science Inc.

引用

页码：139 / 147

页数：8

共 47 条

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