Nasopharyngeal carriage of Haemophilus influenzae

被引：18

作者：

Das B.K. ^{[1
,5
]}

Arora N.K. ^{[2
]}

Mathur P. ^{[1
]}

Ostwal P. ^{[1
]}

Mandal S. ^{[1
]}

Kabra S.K. ^{[2
]}

Kapil A.

Lalitha M.K. ^{[3
]}

Thomas K. ^{[4
]}

机构：

[1] Department of Microbiology, All India Inst. of Medical Sciences, New Delhi

[2] Department of Pediatrics, All India Inst. of Medical Sciences, New Delhi

[3] Dept. of Clinical Microbiology, Christian Medical College Hospital, Vellore

[4] Dept. of Clinical Epidemiology Unit, Christian Medical College Hospital, Vellore

[5] Department of Microbiology, AIIMS

来源：

The Indian Journal of Pediatrics | 2002年 / 69卷 / 9期

关键词：

Colonization; Haemophilus influenzae; Multidrug resistant; Nasopharyngeal carriage;

D O I：

10.1007/BF02723690

中图分类号：

学科分类号：

摘要：

Objective: Nasopharyngeal colonization of Haemophilus influenzae (H. influenzae) in young children may be important in developing countries. Method: In this study, we screened school going children for carriage of H. influenzae. A total of 44 H. influenzae isolates out of a collection of 162 were characterized for biotypes, capsular serotypes and antibiotic resistance. Results: A significant proportion of H. influenzae (25/44) isolates were serotype b. High antibiotic resistance was observed against commonly administered antibiotics like ampicillin (79%), chloramphenicol (20%), trimethoprim sulfamethoxazole (84%) and erythromycin (95%). Comparison of antibiotic resistance profile of nasopharyngeal isolates was observed to be correlated with those of H. influenzae from disease. Conclusion: Multidrug resistant nasopharyngeal H. influenzae in young healthy children may act as reservoir. Monitoring of antibiotic resistance among nasopharyngeal H. influenzae as a surrogate for invasive H. influenzae seems an attractive option.

引用

页码：775 / 777

页数：2

共 27 条

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