Comparison of breast cancer detection by diffusion-weighted magnetic resonance imaging and mammography

被引：58

作者：

Yoshikawa M.I. ^{[1
]}

Ohsumi S. ^{[2
]}

Sugata S. ^{[3
]}

Kataoka M. ^{[3
]}

Takashima S. ^{[2
]}

Kikuchi K. ^{[1
]}

Mochizuki T. ^{[1
]}

机构：

[1] Department of Diagnostic and Therapeutic Radiology, Ehime University Graduate School of Medicine, Shitsukawa

[2] Department of Breast Surgery, National Hospital Organization Shikoku Cancer Center, Matsuyama

[3] Department of Radiology, National Hospital Organization Shikoku Cancer Center, Matsuyama

来源：

Radiation Medicine | 2007年 / 25卷 / 5期

关键词：

Breast cancer; Diffusion-weighted imaging; MRI;

D O I：

10.1007/s11604-007-0128-4

中图分类号：

学科分类号：

摘要：

Purpose. Breast cancer-detecting ability of diffusion-weighted magnetic resonance imaging (DW-MRI) was investigated by comparing the breast cancer detection rates of DW-MRI and mammography (MMG). Materials and methods. The subjects were 48 women who had breast cancer (53 cancer lesions) who underwent DW-MRI before surgery. Altogether, 41 lesions were invasive ductal carcinoma (IDC), 7 were noninvasive ductal carcinoma (NIDC) and 5 were "others." Results. The breast cancer detection rates by MMG and DW-MRI were 84.9% and 94.3% (P < 0.001), respectively. In each classification of histology and size, the detection rate by DW-MRI was higher than that by MMG. In relation to the mammary gland density, the detection rates of fatty, scattered, heterogeneously dense, and extremely dense mammary glands were 100%, 100%, 92.0%, and 83.3%, respectively. The mean apparent diffusion coefficient values of the histologic types were 1.07 ± 0.17 × 10-3, 1.50 ± 0.24 × 10-3, 1.12 ± 0.25 × 10 -3, and 2.01 ± 0.29 × 10-3∈mm 2/s for IDC, NIDC, others, and normal breast, respectively, showing that the values of IDC and NIDC were significantly different from that of the normal breast (P < 0.001 each). A significant difference was also noted between IDC and NIDC (P < 0.001). Conclusion. DW-MRI may be useful for detecting breast cancer in a wide age group of women, including young women with dense mammary glands. © 2007 Japan Radiological Society.

引用

页码：218 / 223

页数：5

共 18 条

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