Assessment of islet function following islet and pancreas transplantation

被引:8
作者
Dy E.C. [1 ]
Harlan D.M. [1 ]
Rother K.I. [1 ]
机构
[1] Diabetes Branch, National Institute of Diabetes, National Institutes of Health, Bethesda, MD 20892
基金
美国国家卫生研究院;
关键词
Islet Transplantation; Pancreas Transplantation; Islet Function; Acute Insulin Response; Insulin Independence;
D O I
10.1007/s11892-006-0067-y
中图分类号
学科分类号
摘要
Pancreas and islet transplant recipients are monitored using various metabolic and imaging methods. The inaccessibility of the transplanted whole pancreas and of the isolated islets poses specific problems (eg, all assessment techniques are indirect). Although successful pancreas transplantation typically restores normal glucose homeostasis, islet transplantation into the liver does not completely normalize islet hormone secretion and glucose metabolism. Development of better testing strategies, such as direct islet imaging, will significantly advance the field. Copyright © 2006 by Current Science Inc.
引用
收藏
页码:316 / 322
页数:6
相关论文
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