Too little exercise and too much sitting: Inactivity physiology and the need for new recommendations on sedentary behavior

被引:575
作者
Hamilton M.T. [1 ]
Healy G.N. [1 ]
Dunstan D.W. [1 ]
Zderic T.W. [1 ]
Owen N. [1 ]
机构
[1] Department of Biomedical Sciences and Dalton Cardiovascular Research Center, University of Missouri, Columbia, MO, 65211
基金
英国医学研究理事会; 美国国家卫生研究院;
关键词
Physical Activity; Sedentary Behavior; Physical Inactivity; Sedentary Time; Physical Activity Guideline;
D O I
10.1007/s12170-008-0054-8
中图分类号
学科分类号
摘要
Moderate-to vigorous-intensity physical activity has an established preventive role in cardiovascular disease, type 2 diabetes, obesity, and some cancers. However, recent epidemiologic evidence suggests that sitting time has deleterious cardiovascular and metabolic effects that are independent of whether adults meet physical activity guidelines. Evidence from "inactivity physiology" laboratory studies has identified unique mechanisms that are distinct from the biologic bases of exercising. Opportunities for sedentary behaviors are ubiquitous and are likely to increase with further innovations in technologies. We present a compelling selection of emerging evidence on the deleterious effects of sedentary behavior, as it is underpinned by the unique physiology of inactivity. It is time to consider excessive sitting a serious health hazard, with the potential for ultimately giving consideration to the inclusion of too much sitting (or too few breaks from sitting) in physical activity and health guidelines. © 2008 Current Medicine Group LLC.
引用
收藏
页码:292 / 298
页数:6
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