A qualitative assessment of factors influencing acceptance of a new rotavirus vaccine among health care providers and consumers

被引:27
作者
Patel M.M. [1 ,5 ]
Janssen A.P. [2 ]
Tardif R.R. [3 ]
Herring M. [4 ]
Parashar U.D. [1 ]
机构
[1] Center for Disease Control, National Center for Immunizations and Respiratory Diseases, Division of Viral Diseases, Atlanta, GA
[2] Center for Disease Control, National Center for Immunizations and Respiratory Diseases, Immunizations Services Division, Atlanta, GA
[3] Oak Ridge Institute for Science and Education, Oak Ridge, TN
[4] Market Directions, Kansas City, MO
[5] Atlanta, GA 30329
关键词
Focus Group; Intussusception; Routine Immunization Schedule; Vaccine Effectiveness Study; Vaccine Information Statement;
D O I
10.1186/1471-2431-7-32
中图分类号
学科分类号
摘要
Background: In 2006, a new rotavirus vaccine (RotaTeq) was licensed in the US and recommended for routine immunization of all US infants. Because a previously licensed vaccine (Rotashield) was withdrawn from the US for safety concerns, identifying barriers to uptake of RotaTeq will help develop strategies to broaden vaccine coverage. Methods: We explored beliefs and attitudes of parents (n = 57) and providers (n = 10) towards rotavirus disease and vaccines through a qualitative assessment using focus groups and in-depth interviews. Results: All physicians were familiar with safety concerns about rotavirus vaccines, but felt reassured by RotaTeq's safety profile. When asked about likelihood of using RotaTeq on a scale of one to seven (1 = "absolutely not;" 7 = "absolutely yes") the mean score was 5 (range = 3-6). Physicians expressed a high likelihood of adopting RotaTeq, particularly if recommended by their professional organizations and expressed specific interest in post-marketing safety data. Similarly, consumers found the RotaTeq safety profile to be favorable and would rely on their physician's recommendation for vaccination. However, when asked to rank likelihood of having their child vaccinated against rotavirus (1 = "definitely not get;" 7 = "definitely get"), 29% ranked 1 or 2, 36% 3 or 4, and 35% 5 to 7. Conclusion: Our qualitative assessment provides complementary data to recent quantitative surveys and suggests that physicians and parents are likely to adopt the newly licensed rotavirus vaccine. Increasing parental awareness of the rotavirus disease burden and providing physicians with timely post-marketing surveillance data will be integral to a successful vaccination program. © 2007 Patel et al; licensee BioMed Central Ltd.
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共 11 条
[1]  
Parashar U.D., Alexander J.P., Glass R.I., Prevention of rotavirus gastroenteritis among infants and children. Recommendations of the Advisory Committee on Immunization Practices (ACIP), MMWR Recomm Rep, 55, RR-12, pp. 1-13, (2006)
[2]  
Vesikari T., Matson D.O., Dennehy P., Van Damme P., Santosham M., Rodriguez Z., Dallas M.J., Heyse J.F., Goveia M.G., Black S.B., Shinefield H.R., Christie C.D., Ylitalo S., Itzler R.F., Coia M.L., Onorato M.T., Adeyi B.A., Marshall G.S., Gothefors L., Campens D., Karvonen A., Watt J.P., O'Brien K.L., DiNubile M.J., Clark H.F., Boslego J.W., Offit P.A., Heaton P.M., Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine, N Engl J Med, 354, 1, pp. 23-33, (2006)
[3]  
Parashar U.D., Hummelman E.G., Bresee J.S., Miller M.A., Glass R.I., Global illness and deaths caused by rotavirus disease in children, Emerg Infect Dis, 9, 5, pp. 565-572, (2003)
[4]  
Intussusception among recipients of rotavirus vaccine - United States, 1998-1999, MMWR Morb Mortal Wkly Rep, 48, 27, pp. 577-581, (1999)
[5]  
Suspension of rotavirus vaccine after reports of intussusception - United States, 1999, MMWR Morb Mortal Wkly Rep, 53, 34, pp. 786-789, (2004)
[6]  
Iwamoto M., Saari T.N., McMahon S.R., Yusuf H.R., Massoudi M.S., Stevenson J.M., Chu S.Y., Pickering L.K., A survey of pediatricians on the reintroduction of a rotavirus vaccine, Pediatrics, 112, 1 PART 1, (2003)
[7]  
Kempe A., Daley M.F., Parashar U.D., Crane L.A., Beaty B.L., Stokley S., Barrow J., Babbel C., Dickinson L.M., Widdowson M.A., Alexander J.P., Berman S., Will pediatricians adopt the new rotavirus vaccine?, Pediatrics, 119, 1, pp. 1-10, (2007)
[8]  
Giacomini M.K., Cook D.J., Users' guides to the medical literature: XXIII. Qualitative research in health care A. Are the results of the study valid? Evidence-Based Medicine Working Group, Jama, 284, 3, pp. 357-362, (2000)
[9]  
Gust D.A., Strine T.W., Maurice E., Smith P., Yusuf H., Wilkinson M., Battaglia M., Wright R., Schwartz B., Underimmunization among children: Effects of vaccine safety concerns on immunization status, Pediatrics, 114, 1, (2004)
[10]  
Meszaros J.R., Asch D.A., Baron J., Hershey J.C., Kunreuther H., Schwartz-Buzaglo J., Cognitive processes and the decisions of some parents to forego pertussis vaccination for their children, J Clin Epidemiol, 49, 6, pp. 697-703, (1996)