Imaging transplant rejection: a new view

被引:10
作者
Cahalan, Michael D. [1 ,2 ]
机构
[1] Univ Calif Irvine, Dept Physiol & Biophys, Irvine, CA 92717 USA
[2] Univ Calif Irvine, Inst Immunol, Irvine, CA USA
关键词
DENDRITIC CELLS; 2-PHOTON MICROSCOPY; LYMPH-NODE; MOTILITY; DYNAMICS;
D O I
10.1038/nm0611-662
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The success of organ transplantation is severely hindered by immune-mediated rejection, but the steps involved in this process remain poorly defined. A new imaging study now reveals the sequence of events and immune cells involved in graft rejection in a mouse model, providing insights into the points at which the immune system could be rationally targeted to prevent transplant rejection (pages 744-749).
引用
收藏
页码:662 / 663
页数:2
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