Familial links between attention deficit hyperactivity disorder, conduct disorder, and bipolar disorder.

被引：32

作者：

Doyle A.E. ^{[1
]}

Faraone S.V. ^{[1
]}

机构：

[1] Massachusetts General Hospital, 15 Parkman Street, ACC-725, Boston, 02114, MA

来源：

Current Psychiatry Reports | 2002年 / 4卷 / 2期

关键词：

Attention Deficit Hyperactivity Disorder; Bipolar Disorder; Conduct Disorder; Attention Deficit Hyperactivity Disorder; Conduct Disorder;

D O I：

10.1007/s11920-002-0049-y

中图分类号：

学科分类号：

摘要：

Although family, twin, and adoption studies indicate that attention deficit hyperactivity disorder (ADHD) is a familial condition with a robust genetic component, molecular genetic studies of candidate genes have produced inconsistent findings. One of the challenges to elucidating the genetic architecture of ADHD is its potential genetic heterogeneity. Therefore, efforts are needed to identify etiologically homogeneous subgroups of subjects with ADHD for use in genetic studies. The current article reviews evidence suggesting that parsing ADHD subjects based on comorbidity with conduct and bipolar disorders may yield familial subtypes that are suitable for genetic analyses.

引用

页码：146 / 152

页数：6

共 160 条

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