The effects of the duration of adaptation to laboratory conditions on the formation of a passive avoidance reflex in rats

被引：2

作者：

Loskutova L.V. ^{[1
]}

Dubrovina N.I. ^{[1
]}

机构：

[1] State Science Res. Inst. of Physiol., Siberian Division, Russian Academy of Medical Sciences, 630117 Novosibirsk

来源：

Neuroscience and Behavioral Physiology | 2004年 / 34卷 / 2期

关键词：

Adaptation; Anxiety; Memory; Passive avoidance;

D O I：

10.1023/B:NEAB.0000009213.40563.7e

中图分类号：

学科分类号：

摘要：

The level of adaptation of rats to their new living conditions was studied during formation of a passive avoidance habit using a single combination. A short acclimation period (3 days) had positive influences on the ability of rats to retain a memory trace. There was a negative correlation between step-through latency and measures of anxiety behavior in the elevated cross maze. A change in the adaptation period to nine days decreased the state of anxiety and the level of performance of the conditioned response. There were no correlations between these measures. The modulating role of the level of adaptation to living conditions, associated with different levels of anxiety, in a passive one-session avoidance learning model was assessed. © 2004 Plenum Publishing Corporation.

引用

页码：189 / 192

页数：3

共 13 条

[1]

Aleksandrova A.A., Polyakova O.N., Batuev A.S., Influence of prenatal stress on learning of rats in the Morris test, Ros. Fiziol. Zh. Im. I. M. Sechenova, 85, 8, pp. 1031-1034, (1999)

[2]

Kaluev A.V., Questions in Studies of Stress Behavior, (1999)

[3]

Loskutova L.V., Kolosova N.G., Emotional status and the ability for one-trial learning in OXYS rats with inherited increases in oxygen radical production, Byull. Éksperim. Biol. Med., 130, 8, pp. 155-158, (2000)

[4]

Trofimov S.S., Ostrovskaya R.U., Voronina T.A., Relationship between the reproducibility of a conditioned passive avoidance reflex and the conditions in which it was acquired in rats, Zh. Vyssh. Nerv. Deyat., 51, 2, pp. 256-261, (2001)

[5]

Beuzen A., Belzung C., Link between emotional memory and anxiety states. A study by principal component analysis, Physiol. Behav., 58, 1, pp. 111-118, (1995)

[6]

Conde C., Costa V., Tomacz C., Measuring emotional memory in the elevated T-maze using a training-to-criterion procedure, Pharmacol. Biochem. Behav., 63, 1, pp. 63-69, (1999)

[7]

Jarvic M.E., Kopp R., An improved one-trial passive avoidance learning situation, Physiol. Rep., 21, pp. 221-224, (1967)

[8]

Lazarus R.S., From psychology of stress to the emotions: A history of changing outlooks, Ann. Rev. Psychol., 44, pp. 1-21, (1993)

[9]

Micheau J., Van Marrewijk B., Stimulation of 5-HT1A receptors by systemic or medial septum injection induces anxiogenic-like effects and facilitates acquisition of a spatial discrimination task in mice, Progr. Neuropsychopharmacol. Biol. Psychiatr., 23, 6, pp. 1113-1133, (1999)

[10]

Pellow S., File S.E., Anxiolytic and anxiogenic effects on exploratory activity in an elevated plus- maze: A novel test of anxiety in the rat, Pharmacol. Biochem. Behav., 24, 3, pp. 525-529, (1986)

← 1 2 →