Neoadjuvant Chemoradiotherapy for Adenocarcinoma of the Pancreas: Treatment Variables and Survival Duration

被引:41
作者
Tara M. Breslin
Kenneth R. Hess
Dana B. Harbison
Marina E. Jean
Karen R. Cleary
Alan P. Dackiw
Robert A. Wolff
James L. Abbruzzese
Nora A. Janjan
Christopher H. Crane
J. Nicolas Vauthey
Jeffrey E. Lee
Peter W. T. Pisters
Douglas B. Evans
机构
[1] The University of Texas M. D. Anderson Cancer Center,Department of Surgical Oncology
[2] The University of Texas M. D. Anderson Cancer Center,Department of Biostatistics
[3] The University of Texas M. D. Anderson Cancer Center,Department of Pathology
[4] The University of Texas M. D. Anderson Cancer Center,Department of Gastrointestinal Oncology
[5] The University of Texas M. D. Anderson Cancer Center,Department of Radiation Oncology
[6] UT M. D. Anderson Cancer Center,Department of Surgical Oncology
关键词
Pancreaticoduodenectomy; Pancreatic cancer; Chemoradiation;
D O I
10.1007/s10434-001-0123-4
中图分类号
学科分类号
摘要
Background:For patients with potentially resectable pancreatic cancer, the poor outcome associated with resection alone and the survival advantage demonstrated for combined-modality therapy have stimulated interest in preoperative chemoradiotherapy. The goal of this study was to analyze the effects of different preoperative chemoradiotherapy schedules, intraoperative radiation therapy, patient factors, and histopathologic variables on survival duration and patterns of treatment failure in patients who underwent pancreaticoduodenectomy for adenocarcinoma of the pancreatic head.
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页码:123 / 132
页数:9
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